Shyam Visweswaran, MD, PhD

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Presentation transcript:

Shyam Visweswaran, MD, PhD Associate Professor of Biomedical Informatics & Intelligent Systems Research Director of Clinical and Translational Informatics Director, Center for Clinical Research Informatics Co-Director, Kimball Family Center for Clinical Informatics Co-Director of Informatics Component, CTSI PD/PI, Precision Medicine Initiative (PA cares for Us) Member, Center for Causal Discovery Training BMI Program Director to MSTP Member, PhD in Clinical and Translational Science Program Committee Leadership Council, (KL2 and TL1 Programs) Past Associate Director, BMI Training Program www.thevislab.com shv3@pitt.edu

Research focuses on different aspects of the Learning Health System Extract, transform, and integrate Apply best evidence for each patient The Learning Health System Molecular and Research Data Kimball Family Center for Clinical Informatics (KCI) Center for Clinical Research Informatics (CCRI) Mobile Health Data Integrated Research Data 1. Learning Electronic Medical Record System 2. Personalized Modeling for Precision Medicine 3. Reuse of EMR Data 4. Precision Medicine Initiative Clinical Decision Support Electronic Medical Records Patient Decision Support

1. Learning Electronic Medical Record System Improve EMRs to intelligently display the right data, at the right time using learning components that adapt both to the medical provider and the patient’s condition. Funding: NLM R01 LM012095 Collaborators: Gregory F. Cooper, Harry Hochheiser, Milos Hauskrecht (Computer Science), Gilles Clermont (Critical Care Medicine), and Dean Sittig (University of Texas)

2. Personalized Modeling for Precision Medicine Facilitate precision medicine with personalized models that enable: more accurate prediction of clinical outcomes, discovery of disease subtypes, and identification of genomic, environmental and clinical factors that are specific to the current individual. Collaborators: Joyeeta Dutta-Moscato (BMI trainee), Gregory F. Cooper, M. Michael Barmada (Human Genetics), David Whitcomb (Gastroenterology & Hepatology)

3. Reuse of EMR Data Enable reuse of Electronic Medical Record (EMR) data for clinical, translational, and informatics research. CTSI-funded i2b2 – based Cohort Discovery Repository NCATS-funded Accrual of patients to Clinical Trials (ACT) network PCORI-funded PaTH clinical data research network (CDRN) Funding: NCATS (NIH) UL1 TR000005 CATS (NIH) UL1 TR000005-09S1 PCORI CDRN 1306-04912 Collaborators: Steven E. Reis (CTSI) and Michael J. Becich

4. Precision Medicine Initiative (PA cares for Us) The PA cares for Us project will enroll 150,000 participants for the Precision Medicine Initiative and will collect EHR data and bio specimens. Funding: UG3 OD023153 Collaborators: Steven E. Reis (CTSI) and Oscar Marroquin (Medicine)