Figure 1 Flow chart distinguishing groups according to receipt of azithromycin treatment and method of data collection. Circles containing the abbreviation.

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Presentation transcript:

Figure 1 Flow chart distinguishing groups according to receipt of azithromycin treatment and method of data collection. Circles containing the abbreviation “Az” indicate the time of mass administration of azithromycin to all children 1–10 years of age as part of an ongoing project described elsewhere [15]. Shaded swab symbol, time nasopharyngeal swab obtained, questionnaire administered, and skin examination performed. “Study period” refers to the present study to determine the secondary effects of mass administration of azithromycin From: Adverse and Beneficial Secondary Effects of Mass Treatment with Azithromycin to Eliminate Blindness Due to Trachoma in Nepal Clin Infect Dis. 2002;35(4):395-402. doi:10.1086/341414 Clin Infect Dis | © 2002 by the Infectious Diseases Society of America

Table 1 Demographic and clinical characteristics of children in 3 groups at baseline (day 0) in study of secondary effects of mass treatment with azithromycin From: Adverse and Beneficial Secondary Effects of Mass Treatment with Azithromycin to Eliminate Blindness Due to Trachoma in Nepal Clin Infect Dis. 2002;35(4):395-402. doi:10.1086/341414 Clin Infect Dis | © 2002 by the Infectious Diseases Society of America

Table 2 Rates of nasopharyngeal carriage and antimicrobial resistance for Streptococcus pneumoniae isolates from children in study of secondary effects of mass treatment with azithromycin From: Adverse and Beneficial Secondary Effects of Mass Treatment with Azithromycin to Eliminate Blindness Due to Trachoma in Nepal Clin Infect Dis. 2002;35(4):395-402. doi:10.1086/341414 Clin Infect Dis | © 2002 by the Infectious Diseases Society of America

Table 3 Proportions of children with impetigo (detected by skin examination) and symptoms of illness (reported during interview) on days 0 and 10 From: Adverse and Beneficial Secondary Effects of Mass Treatment with Azithromycin to Eliminate Blindness Due to Trachoma in Nepal Clin Infect Dis. 2002;35(4):395-402. doi:10.1086/341414 Clin Infect Dis | © 2002 by the Infectious Diseases Society of America

Figure 2 Comparison of proportions of children with symptoms of gastrointestinal illness (reported during interview) and impetigo (detected by skin examination) at days 0, 10, and 180 after administration of azithromycin. NA, not applicable because no nasopharyngeal swabs were obtained at day 10. *P <.05 for comparison with day 0 From: Adverse and Beneficial Secondary Effects of Mass Treatment with Azithromycin to Eliminate Blindness Due to Trachoma in Nepal Clin Infect Dis. 2002;35(4):395-402. doi:10.1086/341414 Clin Infect Dis | © 2002 by the Infectious Diseases Society of America