Volume 59, Issue 6, Pages (December 2013)

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Volume 59, Issue 6, Pages 1323-1330 (December 2013) Management of anemia induced by triple therapy in patients with chronic hepatitis C: Challenges, opportunities and recommendations Manuel Romero-Gómez, Marina Berenguer, Esther Molina, José Luis Calleja Journal of Hepatology Volume 59, Issue 6, Pages 1323-1330 (December 2013) DOI: 10.1016/j.jhep.2013.07.014 Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

Fig. 1 Representation of the mechanism of anemia in patients receiving PegIFN/RBV or protease inhibitor-based triple therapy. A balance between production and lysis is crucial. At the top, equilibrium between lysis and production in healthy people. In the middle, role of ITPA on ribavirin-induced hemolytic anemia, showing an overwhelming lysis. At the bottom, central anemia induced by protease inhibitors in which red cell production is compromised. Journal of Hepatology 2013 59, 1323-1330DOI: (10.1016/j.jhep.2013.07.014) Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

Fig. 2 Management of anemia in patients with chronic hepatitis C genotype 1 receiving protease inhibitor-based triple therapy with telaprevir or boceprevir. Journal of Hepatology 2013 59, 1323-1330DOI: (10.1016/j.jhep.2013.07.014) Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

Journal of Hepatology 2013 59, 1323-1330DOI: (10. 1016/j. jhep. 2013 Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

Journal of Hepatology 2013 59, 1323-1330DOI: (10. 1016/j. jhep. 2013 Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

Journal of Hepatology 2013 59, 1323-1330DOI: (10. 1016/j. jhep. 2013 Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

Journal of Hepatology 2013 59, 1323-1330DOI: (10. 1016/j. jhep. 2013 Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

Journal of Hepatology 2013 59, 1323-1330DOI: (10. 1016/j. jhep. 2013 Copyright © 2013 European Association for the Study of the Liver Terms and Conditions