Copyright © 2017 American Academy of Pediatrics. From: Coronaviruses, Including SARS and MERS Red Book® 2015, 2015 Figure Legend: This scanning electron micrograph (SEM) revealed the thickened, layered edge of severe acute respiratory syndrome-infected Vero E6 culture cells. The thickened edges of the infected cells were ruffled and appeared to comprise layers of folded plasma membranes. Note the layered cell edge (arrows) seen by SEM. Virus particles (arrowheads) are extruded from the layered surfaces. Courtesy of Centers for Disease Control and Prevention Date of download: 12/22/2017 Copyright © 2017 American Academy of Pediatrics. All rights reserved.