Responses to reduced plasma calcium concentration

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Responses to reduced plasma calcium concentration Responses to reduced plasma calcium concentration. Reduced plasma calcium stimulates secretion of PTH. Bone immediately releases calcium from the labile pool into the ECF both stimulated by PTH and independently. PTH also stimulates renal calcium reabsorption and reduces phosphate reabsorption, thereby lowering plasma phosphate and preventing formation of calcium phosphate complexes. On a slower time scale, PTH stimulates osteoclastic bone resorption and increased synthesis of calcitriol from vitamin D in the kidney, leading to increased calcium absorption from the GI tract. Source: Regulation of Calcium, Magnesium, and Phosphate, Vander's Renal Physiology, 8e Citation: Eaton DC, Pooler JP. Vander's Renal Physiology, 8e; 2017 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/2173/eat008_fig_10-02.png&sec=163663815&BookID=2173&ChapterSecID=163663787&imagename= Accessed: November 05, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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