Anna Hallbergson, MD, PhD, Kimberlee Gauvreau, ScD, Andrew J

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Presentation transcript:

Right Ventricular Remodeling After Pulmonary Valve Replacement: Early Gains, Late Losses Anna Hallbergson, MD, PhD, Kimberlee Gauvreau, ScD, Andrew J. Powell, MD, Tal Geva, MD The Annals of Thoracic Surgery Volume 99, Issue 2, Pages 660-666 (February 2015) DOI: 10.1016/j.athoracsur.2014.09.015 Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Diagram of study outline. All 101 patients were included in the cross-sectional analysis. Of those, 47 patients had 2 or more cardiovascular magnetic resonance examinations (CMRs) after pulmonary valve replacement (PVR) and were included in the longitudinal analysis. The Annals of Thoracic Surgery 2015 99, 660-666DOI: (10.1016/j.athoracsur.2014.09.015) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Changes in ventricular size and function and pulmonary regurgitation (PR) after pulmonary valve replacement (PVR). (A) Changes in right ventricular end-diastolic volume index (RVEDVi), right ventricular end-systolic volume index (RVESVi), and PR before and at five time periods after PVR. (B) Changes in right ventricular ejection fraction (RVEF) and left ventricular ejection fraction (LVEF). The Annals of Thoracic Surgery 2015 99, 660-666DOI: (10.1016/j.athoracsur.2014.09.015) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Associations between pre–pulmonary valve replacement (pre-PVR) and post-PVR right ventricular (RV) size and function. (A–C) Correlations between pre-PVR and post-PVR RV end-diastolic volume index (EDVi), end-systolic volume index (ESVi), and ejection fraction (EF). (D–F) Correlations between the same preoperative values and the difference between pre-PVR and post-PVR values. The Annals of Thoracic Surgery 2015 99, 660-666DOI: (10.1016/j.athoracsur.2014.09.015) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Relationships between pre–pulmonary valve replacement (pre-PVR) and post-PVR right ventricular (RV) (A) end-diastolic volume index (EDVi) and (B) ejection fraction (EF). Pre-PVR and post-PVR RV EDVi and EF are grouped according to post-PVR values. The Annals of Thoracic Surgery 2015 99, 660-666DOI: (10.1016/j.athoracsur.2014.09.015) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Pressure and volume loads on the right ventricle before and after pulmonary valve replacement (PVR). The Annals of Thoracic Surgery 2015 99, 660-666DOI: (10.1016/j.athoracsur.2014.09.015) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions