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Douglas L. Mann, MD, Michael A. Acker, MD, Mariell Jessup, MD, Hani N

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Presentation on theme: "Douglas L. Mann, MD, Michael A. Acker, MD, Mariell Jessup, MD, Hani N"— Presentation transcript:

1 Clinical Evaluation of the CorCap Cardiac Support Device in Patients With Dilated Cardiomyopathy 
Douglas L. Mann, MD, Michael A. Acker, MD, Mariell Jessup, MD, Hani N. Sabbah, PhD, Randall C. Starling, MD, Spencer H. Kubo, MD  The Annals of Thoracic Surgery  Volume 84, Issue 4, Pages (October 2007) DOI: /j.athoracsur Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Randomization, treatment, and vital status of patients in the Acorn trial. (CorCap [Acorn Cardiovascular]; MV = mitral valve.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Kaplan-Meier curves for freedom from major cardiac procedures (MCP) in both the cardiac support device treatment and control groups. The treatment group was significantly better than the control group (p = 0.01). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Change in left ventricular (LV) structure in the cardiac support device (CSD) treatment and control groups. (A) Change in LV end-diastolic volume (LVEDV) (mL) from baseline. (B) change in LV end-systolic volume (LVESV) (mL) from baseline. (C) Change in LV ejection fraction (EF) (units) from baseline. (D) Change in LV sphericity index (ratio of LV long axis to LV short axis) at 3, 6, and 12 months. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Change in quality of life scores in the cardiac support device (CSD) treatment and control groups. (A) Change in Minnesota Living with Heart Failure Questionnaire (MLHFQ) score from baseline; (B) change in Short Form-36 Questionnaire (SF-36) score from baseline at 3, 6, and 12 months. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

6 Appendix Fig 1 Graphic output: death or MCP. Sample display. (C = control; LVEDD = left ventricular end-diastolic dimension; MCP = major cardiac procedures; T = treatment). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

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