Abbreviations: GERD, gastroesophageal reflux disease; H2RA, histamine2-receptor agonist; PA, prokinetic agent; PPI, proton-pump inhibitor. Source: Economic Analysis, Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed Citation: Guyatt G, Rennie D, Meade MO, Cook DJ. Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed; 2015 Available at: https://jamaevidence.mhmedical.com/DownloadImage.aspx?image=/data/Books/847/guyatt_ch28-2_fig-28-2-03.jpeg&sec=69034272&BookID=847&ChapterSecID=69031509&imagename= Accessed: October 26, 2017 Copyright © 2017 American Medical Association. All rights reserved