Maintain kidney function for CKD PROBIO-K Complex Powder Maintain kidney function for CKD Copyright © New Bellus Inc. All rights reserved.

Chronic kidney disease Chronic kidney disease (CKD) is a progressive loss in kidney function  over time that can lead to kidney failure, also called end-stage renal disease, ESRD, which requires dialysis or a kidney transplant to maintain life. Another consequence of CKD is that it increases the risk of cardiovascular disease. Chronic kidney disease ESRD

Dialysis Treatment Kidney Transplant Proper Diet or Medication ESRD There is no cure for chronic kidney disease, although treatment can slow or halt the progression of the disease. In the recent years, developing a simple and convenient adjuvant therapy with low risk of side effect has been concerned. PROBIO-K complex powder can help CKD patients to maintain kidney function and reduce the risk of cardiovascular disease

Feature Part I The best three strains providing the best healing efficacy.  Conduct stability assessment to ensure the quality of strains.  All probiotic strains are correct strains by using TAF-certified DAN sequencing method, and are checked using API50 and PFGE strains as QC to avoid contamination and mutations. Has been proved to survive in gastric acid and bile salts environment to reach and colonize in the intestine for proper function.  It has been proved that probiotics have positive effects on inhibiting bad bacteria, preventing inflammatory bowel disease, reversing allergic reaction and regulating immune system, etc. Hence, using probiotics to replace antibiotics or help with treatment could reverse the side effects and improve the efficacy Applied patented 5-layer micro-encapsulation protection.

Feature Part II Complete safety assessment to ensure product cause no harm to human body.  Evaluated by a clinical study. Probiotic strains tested for antibiotic resistance.  Clinically proved to maintain kidney function for chronic kidney disease patients. Reduce the risk of cardiovascular disease.  The study was conducted in cooperation with HungKaung University and Cheng Ching Hospital. Improve the quality of life for chronic kidney disease patients. 

Exclusive Selected Strains Lactobacillus salivarius LS159 Lactococcus lactis subsp. lactis LL358 Lactobacillus pentosus LPE588 The best combination of strains to help with treatment of chronic kidney disease

Lactococcus lactis subsp. lactis LL358 Clinically Proven Lactococcus lactis subsp. lactis LL358

Maintain Kidney Function PROBIO-BAC® PROBIO-K was proved to maintain kidney function for chronic kidney disease. Clinic trial indicated that taking PROBIO-K complex powder would lower blood urea nitrogen level and uric acid. Uric acid (mg/dL) Blood urea nitrogen (mg/dL) Before taking PROBIO-K Taking PROBIO-K for 12 weeks Before taking PROBIO-K Taking PROBIO-K for 12 weeks Note: As kidney function gets worse, the kidney cannot remove blood urea nitrogen and uric acid from blood normally. Fig. The effect of BUN and uric acid change of the third & forth stage CDK patients.

Lower Blood Glucose Levels PROBIO-BAC® PROBIO-K was clinically proved to lower blood glucose levels with 65% of subjects. High blood glucose levels would increase kidney burden, but PROBIO-K was proved to enhance kidney protection. Blood glucose (mg/dL) Before taking PROBIO-K Taking PROBIO-K for 12 weeks Fig. The effect of blood glucose levels of the third & forth stage CDK patients.

Lower Triglyceride Levels PROBIO-BAC® PROBIO-K was clinically proved to lower triglyceride levels with 63% of subjects, reducing the risk of cardiovascular disease. Triglyceride(mg/dL) Before taking PROBIO-K Taking PROBIO-K for 12 weeks Fig. The effect of triglyceride levels of the third & forth stage CDK patients.

The percentage of having improvement Reduce Renal Toxicity PROBIO-BAC® PROBIO-K was clinically proved to lower Indoxyl Sulfate(IS). Indoxyl Sulfate is regarded as a marker of renal dysfunction, also has a substantial role in the progression of CKD. Toxicity The percentage of having improvement IS 40.91% Fig. The percentage of lowering IS levels of the third & forth stage CDK patients.

The percentage of having improvement Improve the Quality of Life PROBIO-BAC® PROBIO-K could help CDK patients to improve symptoms of fatigue, cramp, sleeping difficulty, constipation, dizziness and itchy skin. Symptom The percentage of having improvement Fatigue 52.17% Cramp 47.83% Sleeping difficulty 39.13% Constipation 34.78% Dizziness 30.43% Itchy skin Fig. The improvement of symptoms of the third & forth stage CDK patients.

Patented Technology Patented 5-layer micro-encapsulation protection (Patented No. M479761) Lactic acid bacteria Durable protection Heat-resistant Acid-resistant Bile salt-resistant Lysozyme-resistant, Strong Colonization Proved to survive in gastric acid and bile salts environment to reach and colonize in the intestine.

Certification ISO22000 HACCP GMP Patented No. M479761 HALAL ISO17025

Suitable For  Keep a healthy kidney function  Renal disease patient

Suggested Use 0.1~0.5 g/day (1.0~5.0╳1010CFU/day)

Supporting Document  SPEC  COA  MSDS  HALAL Certification  DNA Verification  Marketing Proposal