LYMPHADENECTOMY IN UROTHELIAL CARCINOMA IN THE RENAL PELVIS AND URETER A RANDOMIZED INTERNATIONAL CLINICAL TRIAL ON LYMPHADENECTOMY IN UROTHELIAL CARCINOMA IN THE RENAL PELVIS AND URETER Next

Inclusion criteria Subjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-up. Age ≥ 18 years Eastern Cooperative Oncology Group (ECOG) status of 0-2. Next

Histological defined UTUC: Histologically confirmed diagnosis of predominantly urothelial carcinoma of the upper urinary tract. Yes Positive biopsy for high grade tumor No Back to start

Histological defined UTUC: Histologically confirmed diagnosis of predominantly urothelial carcinoma of the upper urinary tract. Yes Selective upper tract positive cytology No Back to start

Histological defined UTUC: Histologically confirmed diagnosis of predominantly urothelial carcinoma of the upper urinary tract. Yes Micturition positive cytology (if there is no bladder cancer simultaneously) No Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Next Pelvic or calyx tumor Upper 2/3 of ureter Next Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Yes Absence of fat between pelvis and kidney No Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Yes Evidence of parenchymal invasion No Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Yes Growing of tumor out of the renal pelvis No Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Yes Tumor > 1 cm No Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Yes Growing of the tumor out of the ureter No Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Yes Dilation grade 3-4 No Back to start

Radiological defined UTUC: Patients with UTUC cT2-T4, N0- M0 (TNM classification): Criteria must to be defined by radiologists. Yes Tumor > 1 cm No Back to start

Can not included in the study Back to start

Randomization www.UTUC.dk Back to start