Practical Perspectives in the Surgical Management of Parkinson Disease: LCIG

Introduction

LCIG: Purpose and Function

First Placebo-Controlled Trial of LCIG

LCIG Trial Extension

LCIG Trial Extension (cont)

LCIG: Long-Term Trial

LCIG: Long-Term Trial (cont)

GLORIA Efficacy

GLORIA Safety

LCIG Safety Across 4 Trials

Procedure-Related AEs in Patients Undergoing PEG-J

Non-Device AEs

Continuity of Care

Conclusions

Practical Perspectives in the Surgical Management of Parkinson Disease: DBS

Introduction

DBS Targets

Bilateral STN DBS vs Medical Management: PDQ-39

Bilateral STN DBS vs Medical Management: UPDRS-III

Bilateral STN DBS vs Medical Management: AEs

GPi and STN DBS vs Medical Management: Efficacy

GPi and STN DBS vs Medical Management: Safety

STN vs GPi DBS: CSP 468 at 24 Months

STN vs GPi DBS: CSP 468 at 24 Months (cont)

STN vs GPi: CSP 468 at 36 Months

STN vs GPi DBS

Long-Term Outcomes

DBS Systems

DBS Monitoring

Conclusions

Abbreviations