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Psoriatic Arthritis.

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Presentation on theme: "Psoriatic Arthritis."— Presentation transcript:

1 Psoriatic Arthritis

2 Introduction to PsA

3 Key Cell Types and Activated Pathways in Psoriatic Arthritis

4 Role of IL-17 Signaling

5 Pharmacologic Agents Indicated for the Treatment of PsA

6 FUTURE 1 Efficacy and Safety of Secukinumab

7 FUTURE 2 Efficacy and Safety of SC Secukinumab

8 FUTURE 2: Efficacy of Secukinumab in Anti-TNF-Naive and Anti-TNF-IR Patients

9 FUTURE 5 Improvement in Radiographic Progression

10 Summary of Pooled Safety Across FUTURE 1 and FUTURE 2 Studies

11 Ixekizumab for the Treatment of PsA SPIRIT-P1 Results

12 SPIRIT-P2 Ixekizumab for the Treatment of PsA in TNF-IR Patients

13 Frequency of AEs Across SPIRIT-P1 and SPIRIT-P2 Studies

14 SPIRIT-H2H: Study Comparing Safety and Efficacy of Ixekizumab and Adalimumab in PsA

15 SPIRIT-H2H Results Primary and Secondary Outcomes at Week 24

16 Safety and Efficacy of Bimekizumab in Patients With PsA

17 GRAPPA Treatment Scheme

18 Enthesitis in PsA

19 IL-17 Inhibitors in the Treatment of Enthesitis

20 Dactylitis in PsA

21 IL-17 Inhibitors in the Treatment of Dactylitis

22 MAXIMISE Trial Managing Axial Manifestations in Patients with PsA

23 Concluding Remarks

24

25 Abbreviations

26 Abbreviations (cont)

27 Abbreviations (cont)


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