Jeopardy Final Jeopardy Antacids Antiemetics/ Emetics $100 $100 $100 Proton Pump Inhibitors Antiemetics/ Emetics Laxatives/ Antidiarrheals Safe Nursing Practice $100 $100 $100 $100 $100 $200 $200 $200 $200 $200 $300 $300 $300 $300 $300 $400 $400 $400 $400 $400 $500 $500 $500 $500 $500 Final Jeopardy

1 - $100 The primary goal of daily antacid therapy is the relief of what? Pain

1 - $200 The pain reducing effect of antacids is believed to be due to their what? (list at least 3) Acid-neutralizing capability Inhibition of the protein digesting ability of pepsin Action to increase the resistance of the stomach lining to irritation Ability to increase tone of the LES

1 - $300 What are the three forms of antacids? Aluminum Magnesium Calcium

1 - $400 List the characteristics of both systemic and nonsystemic antacids Systemic – useful in short term therapy, rapid onset, prolonged use causes overload on kidneys Nonsystemic – useful in long term therapy, most of the dose remains in GI tract, will not alter acid base system

1 - $500 List the commonly used antacids and whether they are systemic or nonsystemic Aluminum hydroxide gel- nonsystemic Magnesium hydroxide- nonsystemic Calcium carbonate- nonsystemic Magaldrate- nonsystemic Sodium bicarbonate- systemic

2 - $100 Proton pump inhibitors are indicated for patients with..? List 2 items GERD Gastric hypersecretory condition

2 - $200 What medication do proton pump inhibitors interfere with and what are the possible implications of the interaction? Increase the INR and prothrombin time in patients on Warfarin; could lead to increased risk for bleeding

2 - $300 List the adverse effects of proton pump inhibitors Risk of hip fractures, headaches, abdominal pain, diarrhea, decreased effectiveness of agents that require gastric acidity for absorption

2 - $400 Type answer to appear with a mouse-click here

2 - $500 When should IV dosing of a PPI be discontinued? When the patient is able to take the agent orally

3 - $100 List the 5 categories of antiemetics Anticholinergics Antihistamines Neuroleptic agents Prokinetic agents Serotonin blockers

3 - $200 How do anticholinergics work and what do they prevent? Bind to and block acetylcholine receptors; prevent nausea stimuli from being transmitted

3 - $300 Explain how serotonin blockers work and give an example of one Block serotonin receptors in the GI tract, and CNS (emetic center) Ondansetron (Zofran)

3 - $400 What is the most effective emetic agent available? Activated charcoal

3 - $500 Describe how neuroleptic agents work, list examples, and list adverse affects Bind to dopamine receptors and block action, limit dopamine activity, limit emetic input in the medullary emetic center. Chlorpromazine, droperidol Orthostatic hypotension, sedation, tardive dyskinesia

4 - $100 How do saline laxatives work? List an example of one Increase osmotic pressure within the intestinal tract Magnesium citrate

4 - $200 What can happen if you do not follow bulk forming laxatives with an adequate amount of water? Can cause esophageal obstruction and/ or fecal impaction

4 - $300 Describe how stool softeners work and list examples Permit mixing of fats and fluids with the fecal mass, stool becomes softer and is passed much easier, takes several days to work Docusate salts, Colace, surfak

4 - $400 What things should you encourage patients to do to avoid having constipation? Increased fluid intake, high fiber healthy diet

4 - $500 What two monosaccharides do lactulose laxatives contain? How do they work? What can these be used to treat? Galactose & frusctose Digested in colon by bacteria to form acid substances, cause water to be drawn into the colon Portal systemic encephalopathy

5 - $100 TyMonitor older adults taking H2 receptor antagonists for changes in what? Mental status

5 - $200 Clients taking ranitidine may develop what? What medications does it increase, and what should be monitored? Headache Glipizide, procainamide, theophylline, warfarin effects Lab values should be monitored

5 - $300 What should you monitor in patients taking PPI’s? What should patients taking a PPI avoid? CBC, bone density, liver function Avoid alcohol and OTC products

5 - $400 If vomiting occurs, the nurse’s priority is to prevent aspiration by doing what? Positioning patient in the side lying position

5 - $500 While taking antidiarrheal agents, encourage patients to avoid what? Caffeine, milk products, foods high in fat, fiber, or sugar content

Final Jeopardy Monitor patients receiving palonosetron HCL for what? Changes in QT interval