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Gastrointestinal Drugs

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Presentation on theme: "Gastrointestinal Drugs"— Presentation transcript:

1 Gastrointestinal Drugs

2 Antacids Neutralize stomach acids - cause of heartburn
Active ingredients - aluminum, magnesium hydroxide, calcium carbonate, sodium bicarbonate Bases combine w/ acid to pH Examples Tums Maalox, Mylanta Pepto-Bismal

3 Antacids Adverse effects - constipation, diarrhea
Acid Rebound Phenomenon

4 Histamine (H2) Blockers (Acid Reducers)
Presence of histamine cause the release of gastric acids in stomach Action - prevent (limit) release of histamine by blocking receptor sites Indications acute & chronic ulcers stomach pain GERD

5 H2 Blockers Examples Tagamet (Cimetidine) Pepcid AC (Famotidine)
Zantac 75 (Rantidine) Prilosec – blocks action of H+/K+ ATPase proton pump which secretes acid into the stomach Nexium – new med to treat erosion of esophagus *** Antacids & H2 Blockers should not be a panacea for poor eating habits

6 Antidiarrheal Actions Examples slow peristalsis
adsorbent (absorb H2O & electrolytes) Examples Immodium AD (Loperamide) Donnagel, Kaopectate Pepto-Bismal - antibacterial effects

7 Antiemetics Action - decrease nausea & vomiting Examples
various receptors in CNS to suppress nausea coat the stomach & decrease irritation Examples Phenergan (Promethazine HCl) Benedryl (Diphenhydramine) Dramamine (Dimehydinate) Emetrol - Dextrose, Fructose, Phosphoric Acid Marinol ????

8 Laxatives Examples Drs. recommend non-medicinal remedies
Citracel Metamucil Correctol Milk of Magnesia Drs. recommend non-medicinal remedies Illegal in sports!

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