Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After.

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Presentation transcript:

Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After Myocardial InfarctionClinical Perspective by Adam R. Williams, Konstantinos E. Hatzistergos, Benjamin Addicott, Fred McCall, Decio Carvalho, Viky Suncion, Azorides R. Morales, Jose Da Silva, Mark A. Sussman, Alan W. Heldman, and Joshua M. Hare Circulation Volume 127(2): January 15, 2013 Copyright © American Heart Association, Inc. All rights reserved.

Infarct size reduction after human cardiac stem cell (hCSC) and bone marrow mesenchymal stem cell (hMSC) therapy. Adam R. Williams et al. Circulation. 2013;127: Copyright © American Heart Association, Inc. All rights reserved.

Restoration of left ventricular (LV) function and attenuation of remodeling with human cardiac stem cell (hCSC) and human mesenchymal stem cell (hMSC) therapy. Adam R. Williams et al. Circulation. 2013;127: Copyright © American Heart Association, Inc. All rights reserved.

Impact of human cardiac stem cell (hCSC) and human mesenchymal stem cell (hMSC) therapy on diastolic function. Adam R. Williams et al. Circulation. 2013;127: Copyright © American Heart Association, Inc. All rights reserved.

Preload, afterload, and contractility changes after human cardiac stem cells (hCSC) and human mesenchymal stem cell (hMSCs). Adam R. Williams et al. Circulation. 2013;127: Copyright © American Heart Association, Inc. All rights reserved.

Integrated measures of cardiac performance improve after human cardiac stem cell (hCSC) and human mesenchymal stem cell (hMSC) therapy. Adam R. Williams et al. Circulation. 2013;127: Copyright © American Heart Association, Inc. All rights reserved.

Retention and engraftment of human cardiac stem cells (hCSCs) and human mesenchymal stem cells (hMSCs) in post–myocardial infarction (MI) swine. Adam R. Williams et al. Circulation. 2013;127: Copyright © American Heart Association, Inc. All rights reserved.