Clinical Data Exchange using HL7 and Mirth Connect Lecture 2 - Toolset to use for working with Mirth Connect. - Mirth Connect architecture. - Changing the internal database engine used by Mirth Connect. Siv Raman, MD, MS

Toolset for working with Mirth Connect HL7 Inspector Open-source and free software tool for sending and receiving HL7 messages. Accommodates protocols like MLLP. http://sourceforge.net/projects/hl7inspector/ An alternative to using HL7 Inspector is the toolset available at http://nule.org Stunnel Open-source and free multi-platform SSL tunneling proxy that allows secure, encrypted HL7 interfaces to be set up. Mirth Connect does not support encrypted interfaces out of the box. http://www.stunnel.org/ PostgreSQL Open-source and free relational database management system. http://www.postgresql.org/ soapUI Functional Testing tool for Web Service Testing. It supports multiple protocols such as SOAP, REST, HTTP, JMS, ... http://www.soapui.org/

Toolset for working with Mirth Connect, continued Apache ActiveMQ An open-source and free complete message broker and full Java Message Service (JMS) 1.1 provider. It provides "Enterprise Features" like clustering, multiple message stores, and ability to use any database as a JMS persistence provider besides Virtual Machine (VM), cache, and journal persistency. http://activemq.apache.org/ SQuirrel SQL Open-source and free Java SQL Client program for any JDBC compliant database. http://squirrel-sql.sourceforge.net/ Java Runtime Environment (JRE) The runtime environment for Java 6 (1.6) or later. Since Mirth Connect is written mostly in Java, the JRE is required to make it work. http://www.java.com/en/download/ Notepad++ Open-source and free text-editor http://notepad-plus-plus.org/ Mirth Connect 2.1.1 http://www.mirthcorp.com/community/downloads

Mirth Connect Architecture Mirth Connect Server Mirth Connect API Mirth Connect Administrator Message Store Mirth Connect Command Line Interface Enterprise Service Bus Connector Plug-ins Health Information System

Mirth Connect Architecture, continued Written mostly in Java Uses the Mule Enterprise Service Bus (ESB) Customized routing engine for broadcast/router modes Connectors (SFTP, LLP, Document Writer) Additional connectors can be easily added Uses the HAPI HL7 v2 parser for strict HL7 parsing For strict parsing only http://hl7api.sourceforge.net/ Uses a different HL7 v2 parser for non-strict parsing Includes X12, EDI parsers Includes the Rhino JavaScript Engine with E4X (ECMAScript for XML) support (http://www.mozilla.org/rhino/) Internal XML engine for message transformation Server RESTful interface Extensible on other platforms (.NET, Web) Custom code extensions can be loaded through new JAR packages

Mirth Connect Architecture, continued Mirth Connect database stores data for messages, channels, users, events, configuration, etc. Open source version of Mirth Connect uses Apache Derby database Performance decreases at about 100,000 messages Not recommended for production use if storing message data Mirth Connect can be configured to use other databases as its internal database PostgreSQL, Oracle, MySQL, SQL Server officially supported Create mirthdb database using the database server admin tool. Mirth Connect Server will automatically create schema and tables if they don't exist A database to connect to should already be created, but can be empty Back up server configuration before changing Select database and set attributes using Mirth Connect Server Manager Or directly edit mirth.properties in conf folder of the Mirth Connect install directory Data will remain on old database schema Restart the Mirth Connect Service PostgreSQL is recommended database for production environments Used on Mirth Appliances Powerful open source database solution

E4X (ECMAScript for XML) https://developer.mozilla.org/index.php?title=En/Core_JavaScript_1.5_Guide/Processing_XML_with_E4X http://www.xml.com/pub/a/2007/11/28/introducing-e4x.html http://www.w3schools.com/e4x/default.asp http://en.wikipedia.org/wiki/ECMAScript_for_XML