CAMPBELL BIOLOGY Reece Urry Cain Wasserman Minorsky Jackson © 2014 Pearson Education, Inc. TENTH EDITION 1 Evolution, the Themes of Biology, and Scientific Inquiry Lecture Presentation by Nicole Tunbridge and Kathleen Fitzpatrick

Inquiring About Life An organism’s adaptations to its environment are the result of evolution For example, the seeds of the dandelion are moved by wind due to their parachute-like structures Evolution is the process of change that has transformed life on Earth

Biology is the scientific study of life Biologists ask questions such as How does a single cell develop into an organism? How does the human mind work? How do living things interact in communities? Life defies a simple, one-sentence definition Life is recognized by what living things do

Figure 1.2 Order Energy processing Growth and development Regulation Reproduction Response to the environment Evolutionary adaptation

Concept 1.1: The study of life reveals common themes Biology is a subject of enormous scope There are five unifying themes Organization Information Energy and matter Interactions Evolution

Theme: New Properties Emerge at Successive Levels of Biological Organization Life can be studied at different levels, from molecules to the entire living planet This enormous range can be divided into different levels of biological organization

Figure The Biosphere 7 Tissues 8 Cells 5 Organisms 10 Mole- cules 3 Communities 2 Ecosystems 6 Organs and Organ Systems 4 Populations 9 Organelles

Emergent Properties Emergent properties result from the arrangement and interaction of parts within a system Emergent properties characterize nonbiological entities as well For example, a functioning bicycle emerges only when all of the necessary parts connect in the correct way

Reductionism is the reduction of complex systems to simpler components that are more manageable to study For example, studying the molecular structure of DNA helps us to understand the chemical basis of inheritance

To explore emergent properties, biologists complement reductionism with systems biology, analysis of the interactions among the parts of a biological system

Structure and Function At each level of the biological hierarchy we find a correlation between structure and function

The Cell: An Organism’s Basic Unit of Structure and Function The cell is the lowest level of organization that can perform all activities required for life Every cell is enclosed by a membrane that regulates passage of materials between the cell and its environment

A eukaryotic cell has membrane-enclosed organelles, the largest of which is usually the nucleus By comparison, a prokaryotic cell is simpler and usually smaller, and does not contain a nucleus or other membrane- enclosed organelles

Figure 1.4 Eukaryotic cell Membrane Cytoplasm Membrane- enclosed organelles Nucleus (membrane- enclosed) DNA (throughout nucleus) 1 µm Prokaryotic cell Membrane DNA (no nucleus)

Each DNA molecule is made up of two long chains arranged in a double helix Each chain is made up of four kinds of chemical building blocks called nucleotides and nicknamed A, G, C, and T

Figure 1.6 Sperm cell Egg cell Fertilized egg with DNA from both parents Embryo’s cells with copies of inherited DNA Offspring with traits inherited from both parents Nuclei containing DNA

Each DNA molecule is made up of two long chains arranged in a double helix Each chain is made up of four kinds of chemical building blocks called nucleotides and nicknamed A, G, C, and T

Figure 1.7 Nucleus DNA (a) DNA double helix (b) Single strand of DNA A T G G T A T A C A C T A C Nucleotide Cell

Each DNA molecule is made up of two long chains arranged in a double helix Each chain is made up of four kinds of chemical building blocks called nucleotides and nicknamed A, G, C, and T

Genes control protein production indirectly DNA is transcribed into RNA, which is then translated into a protein Gene expression is the process of converting information from gene to cellular product

Genomics: Large-Scale Analysis of DNA Sequences An organism’s genome is its entire set of genetic instructions The human genome and those of many other organisms have been sequenced Genomics is the study of sets of genes within and between species Proteomics is the study of whole sets of proteins encoded by the genome (known as proteomes)

Theme: Life Requires the Transfer and Transformation of Energy and Matter The input of energy from the sun and the transformation of energy from one form to another make life possible When organisms use energy to perform work, some energy is lost to the surroundings as heat As a result, energy flows through an ecosystem, usually entering as light and exiting as heat

Figure 1.9 ENERGY FLOW Light energy Heat Chemical energy Plants take up chemicals from the soil and air. Chemicals Decomposers return chemicals to the soil. Chemicals pass to organisms that eat the plants.

Ecosystems: An Organism’s Interactions with Other Organisms and the Physical Environment At the ecosystem level, each organism interacts continuously with other organisms These interactions may be beneficial or harmful to one or both of the organisms Organisms also interact continuously with the physical factors in their environment, and the environment is affected by the organisms living there

Figure 1.10 Sunlight Leaves take in carbon dioxide from the air and release oxygen. Animals eat leaves and fruit from the tree, returning nutrients and minerals to the soil in their waste products. Water and minerals in the soil are taken up by the tree through its roots. Leaves absorb light energy from the sun. Leaves fall to the ground and are decomposed by organisms that return minerals to the soil. CO 2 O2O2

Molecules: Interactions Within Organisms Interactions between components—organs, tissues, cells, and molecules—that make up living organisms are crucial to their smooth operation Cells are able to coordinate various chemical pathways through a mechanism called feedback

Figure 1.11 Insulin Circulation throughout body via blood Insulin-producing cell in pancreas STIMULUS: High blood glucose level Negative feedback Liver and muscle cells RESPONSE: Glucose uptake by liver and muscle cells

In feedback regulation the output, or product of a process, regulates that very process The most common form of regulation in living organisms is negative feedback, in which the response reduces the initial stimulus Feedback is a regulatory motif common to life at all levels

Evolution, the Core Theme of Biology Evolution is the one idea that makes logical sense of everything we know about living organisms The scientific explanation for both the unity and diversity of organisms is the concept that living organisms are modified descendants of common ancestors Many kinds of evidence support the occurrence of evolution

Concept 1.2: The Core Theme: Evolution accounts for the unity and diversity of life “Nothing in biology makes sense except in the light of evolution”— Theodosius Dobzhansky Evolutionary mechanisms account for the unity and diversity of all species on Earth

The Three Domains of Life Organisms are divided into three domains, named Bacteria, Archaea, and Eukarya Domain Bacteria and domain Archaea compose the prokaryotes

Figure 1.13 (a) Domain Bacteria (c) Domain Eukarya 2 µm (b) Domain Archaea 2 µm 100 µm Kingdom Animalia Kingdom Plantae Kingdom Fungi Protists

Domain Eukarya includes all eukaryotic organisms Domain Eukarya includes three multicellular kingdoms Plants, which produce their own food by photosynthesis Fungi, which absorb nutrients Animals, which ingest their food

Other eukaryotic organisms were formerly grouped into the Protist kingdom, though the recent trend has been to split the protists into several kingdoms

Unity in the Diversity of Life A striking unity underlies the diversity of life; for example DNA is the universal genetic language common to all organisms Unity is evident in many features of cell structure

Charles Darwin and the Theory of Natural Selection Fossils and other evidence document the evolution of life on Earth over billions of years

Charles Darwin published On the Origin of Species by Means of Natural Selection in 1859 Darwin made two main points Species showed evidence of “descent with modification” from common ancestors “Natural selection” is the mechanism behind descent with modification Darwin’s theory explained the duality of unity and diversity

Darwin inferred that Individuals that are best suited to their environment are more likely to survive and reproduce Over time, more individuals in a population will have the advantageous traits Evolution occurs as the unequal reproductive success of individuals

In other words, the environment “selects” for the propagation of beneficial traits Darwin called this process natural selection

Figure Population with varied inherited traits Elimination of individuals with certain traits 12 Reproduction of survivors 3 Increasing frequency of traits that enhance survival 4

Natural selection results in the adaptation of organisms to their environment For example, bat wings are an example of adaptation

Figure 1.19

Darwin proposed that natural selection could cause an ancestral species to give rise to two or more descendent species For example, the finch species of the Galápagos Islands are descended from a common ancestor Evolutionary relationships are often illustrated with treelike diagrams that show ancestors and their descendants

Figure 1.20 Green warbler finch COMMON ANCESTOR Certhidea olivacea Gray warbler finch Certhidea fusca Sharp-beaked ground finch Geospiza difficilis Vegetarian finch Platyspiza crassirostris Mangrove finch Cactospiza heliobates Woodpecker finch Cactospiza pallida Medium tree finch Camarhynchus pauper Large tree finch Camarhynchus psittacula Small tree finch Camarhynchus parvulus Large cactus ground finch Geospiza conirostris Cactus ground finch Geospiza scandens Small ground finch Geospiza fuliginosa Medium ground finch Geospiza fortis Large ground finch Geospiza magnirostris Cactus-flower- eaters Seed-eaters Ground finches Tree finches Insect-eaters Bud- eater Seed- eater Insect-eatersWarbler finches

Concept 1.3: In studying nature, scientists make observations and form and test hypotheses The word science is derived from Latin and means “to know” Inquiry is the search for information and explanations of natural phenomena The scientific process includes making observations, forming logical hypotheses, and testing them

Making Observations Biologists describe natural structures and processes This approach is based on observation and the analysis of data Recorded observations are called data Qualitative data often take the form of recorded descriptions Quantitative data are generally expressed as numerical measurement, organized into tables and graphs

Inductive reasoning draws conclusions through the logical process of induction Repeating specific observations can lead to important generalizations For example, “the sun always rises in the east”

Forming and Testing Hypotheses In science a hypothesis is a tentative answer to a well-framed scientific question It is usually a rational accounting for a set of observations It leads to predictions that can be tested by making additional observations or by performing experiments

Figure 1.22 Observation: Flashlight doesn’t work. Question: Why doesn’t the flashlight work? Hypothesis #1: Batteries are dead. Hypothesis #2: Bulb is burnt out. Prediction: Replacing bulb will fix problem. Test of prediction: Replace bulb. Result: Flashlight works. Hypothesis is supported. Result: Flashlight doesn’t work. Hypothesis is contradicted. Test of prediction: Replace batteries. Prediction: Replacing batteries will fix problem.

Deductive Reasoning Deductive reasoning uses general premises to make specific predictions Initial observations may give rise to multiple hypotheses We can never prove that a hypothesis is true, but testing it in many ways with different sorts of data can increase our confidence in it tremendously

Questions That Can and Cannot Be Addressed by Science A hypothesis must be testable and falsifiable For example, a hypothesis that ghosts fooled with the flashlight cannot be tested Supernatural and religious explanations are outside the bounds of science

The Flexibility of the Scientific Process The scientific method is an idealized process of inquiry Hypothesis-based science is based on the “textbook” scientific method but rarely follows all the ordered steps Backtracking and “rethinking” may be necessary part way through the process