Plague Black Death Black Plague Bubonic Plague Pestilence

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The Black Death of the Middle Ages The Bubonic Plague

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Presentation transcript:

Plague Black Death Black Plague Bubonic Plague Pestilence The Great Plague

Three Types of Plague Bubonic Plague Pneumonic Plague Septicemia Plague (blood infection)

Bubonic Plague Caused by bacteria: Yersinia pestis Carried by fleas – that live on rodents - often rats (can be dogs, cats, squirrels, etc.) During the 1300’s; One quarter of the population of Europe died. Mortality = 30-75%

Pneumonic Plague Caused by bacteria: Less common than Bubonic plague Yersinia pestis Less common than Bubonic plague Most victims die Mortality 90-95% Infects the lungs “Sheepshearer’s Disease”

Septicemia Plague Rarest of all plagues Mortality near 100% Even today no treatment “DIC” = disseminated intravascular coagulation

Septicemia Victim

Bubonic Plague Victim Bubo = tender swollen area, often in the groin area or in the armpit. Also appears in area where flea has bitten victim “Bubo”

Bubonic

The Black Death Victim recovering from Bubonic Plague At one time his entire body was black

Black Death Victim Same victim Toes have gangrene Probably will have to be amputated

Mammalian Victim Pneumonic plague Rock squirrel in Colorado Coughing up sputum from pneumonic plague

Death Toll Most historians agree that the Black Death killed between 30-45% of the European population between 1348 & 1350 25 million people died between 1347 & 1352

CCR5 gene – Delta 32 Mutation Located on Chromosome 3 Some people inherit one or two of these Dd or dd Heterozygous or Homozygous Recessive Provided resistance against the plague Now provides resistance against HIV

CCR5 codes for White Blood Cell

CCR5 Mutation % Europe

CCR5 Mutation = World

News of the Week … Bubonic Plague In 2015? Madagascar's Current Plague More Virulent Than Strain From Dark Ages Jan 28, 2015 03:53 PM By Dana Dov No, you did not misread the headline to this story. Not only does the bubonic plague still exist, but it’s infected hundreds of individuals on the island of Madagascar, off the coast of Africa. In fact, this is nearly an annual occurrence for the island nation. Unlike the plague of the past, however, this form is not only harder to contain but can kill nearly 24 hours after initial exposure.

Secrets of the Dead: Black Plague https://vimeo.com/55035270

Black Plague Kristie Kazimir and Alex Bester http://www.youtube.com/watch?v=bbAJSGPOv6A