Research & Development 2016 RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust.

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Presentation transcript:

Research & Development 2016 RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Types of Investigation Audit Are we doing this to an accepted standard? Contact the Audit dept. Service Evaluation How do we do this in the hospital at the moment? Contact Research What is the best way of doing this? Contact

2016 We are involved in many research studies covering a wide variety of specialities, here are just a few: CancerStroke RheumatologyDiabetes MusculoskeletalMedicines for children NeurologicalCritical Care PainDermatology SurgeryChildren GastroOphthalmology RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Clinical Trials Phases 1 & 2 Phase 1 (safety and tolerability) trials which involve first human exposure to a therapeutic agent. Phase 2 clinical trials are primarily intended to demonstrate whether or not the new drug will provide any benefit and whether that benefit is sufficiently better than standard treatments to warrant further development. RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Clinical Trials Phases 3 & 4 Phase 3 trials compare new treatments with the best currently available treatment. They usually involve many more patients than phase 1 or 2. This is because differences in success rates may be small. This is the kind of study that patients from this hospital are most often recruited into. Phase 4 trials involve the safety surveillance and on-going technical support of a drug after it receives permission to be sold. RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Research for Patient Benefit at West Suffolk Foundation Trust The Research Question Does giving patients a 5mg transdermal Glyceryl trinitrate (GTN) patch as soon as possible after a stroke improve patient outcome? The RIGHT-2 Trial: Dr A Azim Stroke Services, West Suffolk Hospital RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Medicinal Plants Senna alexandrina a source of senna RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Cancer Research at West Suffolk Foundation Trust The Research Question Does taking aspirin regularly after treatment for early stage cancer stop or delay the cancer coming back? The ADD-ASPIRIN Trial: Dr D Patterson Dept. of Oncology, West Suffolk Hospital RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

RESEARCH & DEVELOPMENT, WEST SUFFOLK HOSPITAL Medicinal Plants Salix alba a source of Aspirin RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Rheumatology Research at West Suffolk Foundation Trust The Research Question How many people are affected by sight loss in giant cell arteritis every year? Are any particular patients at risk of sight loss? GCA SIGHT LOSS Study: Dr David O’Reilly Dept. of Rheumatology, West Suffolk Hospital RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Cancer Research at West Suffolk Foundation Trust What is the best therapy for advanced or metastatic prostate cancer? The STAMPEDE trial Researcher: Dr Cathryn Woodward Dept. of Oncology West Suffolk Hospital RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Medical Device Research at West Suffolk Hospital The Research Question Is the i-gel (second-generation Supraglottic airway device) superior to tracheal intubation in non-traumatic out of hospital cardiac arrest in adults? The AIRWAYS 2 Trial: Sally Humphreys Critical Care, West Suffolk Hospital RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Diabetes Research at West Suffolk Foundation Trust A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to Prevent Type 2 Diabetes in India and the UK The SMS Study: Dr J Clark Dept. of Diabetes, West Suffolk Hospital RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Medicinal Plants Madagascar Periwinkle a source of Vincristine RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Let R&D take the strain! Contact: RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Health Technology Devices (HTD) The Health Technology Devices Programme aims to stimulate and promote collaborative research that contributes towards the development of new technology which meets patient needs. The HTD programme focuses on supporting the development of new medical devices and healthcare technologies that are capable of exploitation by the healthcare industries. HTD Calls are invited and handled through the HTD web portal at: RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Clostridium botulinum source of Botox RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

West Suffolk Foundation Trust Research Aim To ensure that all patients and healthcare professionals from all areas of healthcare can take part in and benefit from clinical research RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Funding Programmes Programme Grants for Applied Research Programme Development Grant Funding Projects Research for Patient Benefit (RfPB) Research for Innovation Speculation and Creativity (RISC) Invention for Innovation Programme (i4i) HTA Clinical Trials Health Technology Devices (HTD) RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

The First Clinical Trial in 1747 James Lind compared six treatments for scurvy (non-randomised open label) Two patients were given cider Two elixir vitriol Two vinegar Two sea water Two spices, garlic & mustard seeds Two oranges and lemons Only the sailors given the fruit recovered It took 40 years for the Admiralty to issue lemon juice to all ships RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

Research Grants Research for Innovation Speculation and Creativity (RISC) RISC is a response-mode funding programme established to provide research of direct benefit to users of the NHS in England. The RISC programme is for potentially paradigm-changing projects in Health Services and Public Health Research. RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust

HTA Clinical Trials The HTA programme commissions research in three different ways: 1. By advertising standard calls for research proposals that address specific topics 2. By advertising special calls for research proposals that address themed areas 3. By funding HTA clinical trials and evaluation studies that are proposed directly by researchers. RESEARCH & DEVELOPMENT, West Suffolk Foundation Trust