1. Normal RBC

4. Variation in Normal

8. Rubriblast

9. Prorubricyte

11. Rubricyte

12. Metarubricyte

13. Reticulocyte

14. RBC

15. Copyright ©2001 American Society of Hematology. Copyright restrictions may apply. Rubriblast or Pronormoblast (Proerythroblast)

16. Prorubricyte (Basophilic Normoblast)

17. Copyright ©2005 American Society of Hematology. Copyright restrictions may apply. Maslak, P. ASH Image Bank 2005;2005:101351 Prorubricyte or Basophilic Normoblast

18. Rubricyte (Polychromatophilic Normoblast)

19. Copyright ©2004 American Society of Hematology. Copyright restrictions may apply. Maslak, P. ASH Image Bank 2004;2004:101152 Rubricyte or Polychromatophilic Normoblast

20. Metarubricyte

21. Metarubricyte, nucleus ejected

22. Polychromasia

28. Normochromic/Normocytic v. Hypochromic/Microcytic

29. Normal v IDA Maturation

30. Iron Deficiency Anemia (IDA)

31. IDA

33. Iron deficient

34. Hypochromic RBCs

35. Hypochromic, Microcytic

36. IDA, treated

37. Anemia of Chronic Disease http://www.brainshark.com/brainshark/vu/view.asp?pi=35105778 http://www.brainshark.com/brainshark/vu/view.asp?pi=35105778

38. Normal B12 or Folate Deficient

39. Normocytic v. Macrocytic

40. Normal v B12/Folate Deficiency Maturation

41. Folate Deficiency, Bone Marrow

42. Megaloblastic Anemia, Bone Marrow

46. Macro Ovalocytes

47. B12/Folate

48. Hypersegmented PMN

49. B12/Folate Deficiency

50. Pernicious Anemia

51. Megaloblastic Anemia

52. Hypochromic/Microcytic Normochromic/Normocytic Macrocytic(/Normochromic)

53. Macrocytic, Microcytic Normocytic

54. Copyright ©2005 American Society of Hematology. Copyright restrictions may apply. Gallagher, P. G. Hematology 2005;2005:13-18 Figure 2. Pathophysiology of hereditary spherocytosis

55. Hereditary Spherocytosis

56. Normal v. Spherocytosis

57. Spherocytosis

58. Spherocytes

59. Normal v Ovalocyte

60. Hereditary Ovalocytosis

61. Eliptocytosis

62. Hereditary Stomatocytosis

63. Stomatocytosis

64. Cut by Fibrin Strands

65. Membrane damaged RBCs

66. Schistocytes

68. Microangiopathic Hemolytic Anemia (MAHA)

69. Burr Cells (Crenated Cells) Thorn Cells Acanthocytes

70. 1. 1. Ovalo (green label): normochromic/normocytic ovalocytes. 80%+ are ovalocytes 2. H. Ovalo or Review Hered Ovalo: another case. normochromic/normocytic ovalocytes. 80%+ are ovalocytes 3. Hered Sphero: Many spherocytes 4. Hypo Micro: hypochromic microcytes, few hypochronic ovalocytes,occaisional hypochromic teardrop 5: IDA MCV 46 Hgb 3.8: hypochromic microcytes, hypochromic ovalocytes, hypochromic teardrops 6. B12/Folate 0671264 1993: macrocycytic normochromic RBCs. Well filled with hgb. Few macrocytic ovalocytes, occ hyperseg PMN 7: H-J MCV 121: normochromic macrocytes. H-J bociesfew macrocytic target cells 8. B12/Folate: Many hpersegmented PMNs Normochromic macrocytes 9. NRBC: Many nucleated RBCs, mostly metarubricytes 10. ABO HDN: hemolytic disease of the newborn. Earlies stages of nrbc including prorubricyte and rubricyte 11. Mono: increased monocytes 12. EOS increased eosinophils 13. 75% EOS: increased eosinophils 14. Schisto Acantho: Many schistocytes and acanthocytes 15. 09009291992: ?? Mystery slide. What do you see

71. http://www.clt.astate.edu/wwilliam/hem_i_erythrocytes_morphology_and__physiology.htm

72. END