1. Exercise 1 DNA identification

2. To which population an individual belongs? Two populations of lab-mice have been accidentally put in a same cage. Your job is to sort the two populations to separate cages as precisely as possible. There were 50 individuals in population 1, and 10 individuals in population 2. You pick randomly a mouse from the mixed population and apply a genetic test which reveals the genotype of the mouse in terms of two independent microsatellite loci The allele frequencies in the two populations are known to be the following:

3. Allele frequencies Locus 1Locus 2 Population 1A: 40% B: 60% a:30% b:70% Population 2A: 80% B: 20% a:10% b:90%

4. Classify the mouse… Before knowing the result of the test, what is the probability that the mouse belongs to population 1? What is the probability that the genotype in Locus 1 will be AA? Analysis of the first locus shows that the genotype of the mouse is AA. What is the probability that the mouse belongs to population 1? Next, you will analyze locus 2. What is the probability that you will find genotype bb? The genotype in locus 2 seems to be bb. What is the probability that the mouse belongs to population 1?