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Published bySpencer Wilfrid Simmons Modified over 4 years ago

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Hardy Weinberg

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Hardy Weinberg refers to Populations

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Hardy Weinberg Equilibrium What it is? A way to measure evolution in a population Allele frequency will not change from generation to generation if a population is not evolving.

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These are your alleles Genotype? Bb

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Phenotype? What is the allele frequency in the room?

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Let’s set up a data table to record our allele frequencies.

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Let’s Reproduce... Meiosis Anyone? Then into the gene pool This is more like spawning

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What is our new allele frequency?

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1. Natural Selection 2. Calculate survivor allele frequency 3. SURVIVORS only...Reproduce 4. Next generation

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H-W Equilibrium says Allele Frequency will remain the same from generation to generation... DID IT?

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Oh Wait... Hardy Weinberg Conditions 1. No mutation 2. Random Mating 3. Large Population 4. No Natural Selection 5. No emigration/immigration

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Science Practice 1 The student can use representations and models to communicate scientific phenomena and solve scientific problems. Model : Reproductive isolation.

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Model: genetic drift Model: non-random mating Model: mutation Model: emigration/immigration

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How do we use the H-W Formula? p 2 + 2pq + q 2 = 1

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19 Hardy-Weinberg describes the status quo and provides a way to describe change. 5 conditions must be met: Allele frequencies won’t change if… 1. The population is large 2. Mating is random 3. There is no mutation 4. No immigration or emigration 5. There is no selection

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20 All the alleles in a population must equal 100% Say A and a are the alleles at a locus Diploid organisms have 2 loci p = the frequency of A q = the frequency of a So the frequency of p + q must equal 100% or 1.0

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21 Frequency of possible combinations of p and q for diploid organisms (p+q) (p+q) =(p+q) (p+q) = p 2 + 2pq + q 2

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In a population of 1000 individuals, 360 of the individuals have an attached earlobe, a recessive trait. This population is in Hardy Weinberg equilibrium. How many individual are heterozygous for this trait?

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Scotland has the highest percentage of redheads in the world at 13%. Assuming Hardy Weinberg equilibrium, calculate the frequency of p and q.

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