# Hardy Weinberg. Hardy Weinberg refers to Populations.

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Hardy Weinberg

Hardy Weinberg refers to Populations

Hardy Weinberg Equilibrium What it is? A way to measure evolution in a population Allele frequency will not change from generation to generation if a population is not evolving.

These are your alleles Genotype? Bb

Phenotype? What is the allele frequency in the room?

Let’s set up a data table to record our allele frequencies.

Let’s Reproduce... Meiosis Anyone? Then into the gene pool This is more like spawning

What is our new allele frequency?

1. Natural Selection 2. Calculate survivor allele frequency 3. SURVIVORS only...Reproduce 4. Next generation

H-W Equilibrium says Allele Frequency will remain the same from generation to generation... DID IT?

Oh Wait... Hardy Weinberg Conditions 1. No mutation 2. Random Mating 3. Large Population 4. No Natural Selection 5. No emigration/immigration

Science Practice 1 The student can use representations and models to communicate scientific phenomena and solve scientific problems. Model : Reproductive isolation.

Model: genetic drift Model: non-random mating Model: mutation Model: emigration/immigration

How do we use the H-W Formula? p 2 + 2pq + q 2 = 1

19 Hardy-Weinberg describes the status quo and provides a way to describe change. 5 conditions must be met: Allele frequencies won’t change if… 1. The population is large 2. Mating is random 3. There is no mutation 4. No immigration or emigration 5. There is no selection

20 All the alleles in a population must equal 100% Say A and a are the alleles at a locus Diploid organisms have 2 loci p = the frequency of A q = the frequency of a So the frequency of p + q must equal 100% or 1.0

21 Frequency of possible combinations of p and q for diploid organisms (p+q) (p+q) =(p+q) (p+q) = p 2 + 2pq + q 2

In a population of 1000 individuals, 360 of the individuals have an attached earlobe, a recessive trait. This population is in Hardy Weinberg equilibrium. How many individual are heterozygous for this trait?

Scotland has the highest percentage of redheads in the world at 13%. Assuming Hardy Weinberg equilibrium, calculate the frequency of p and q.

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