1. Classic Lattice Degeneration

2. Perivascular Lattice

3. Photocoagulation spots in moderate pattern

4. Cryotherapy

6. Vitreous Anomoly

7. Attached with Silicone Oil

8. Early diagnosis and intervention for retinal detachments can preserve vision. Stickler GB, Hughes W, Houchin P. Clinical features of hereditary progressive arthro-ophthalmopathy (Sticklersyndrome): a survey. Genet Med. 2001 May-Jun;3(3):192-6.

9. Retinal Detachment and Prophylaxis in Type 1 Stickler Syndrome GroupRetina Detachment Bilateral RDFollow –Up (years) No Treatment 73%48%21 Bilateral Treatment 8%0%11.5 Unilateral Treatment 10% 15.5 Ang A, Poulson AV, Goodburn SF, Richards AJ, Scott JD, Snead MP.Ophthalmology. 2008 Jan;115(1):164-8.

10. Shapiro Recommendation Monitor Q 3 months to catch RD early EUAs as needed to get view of periphery Test each eye regularly Educate for Signs of breaks and RDs Educate of continued high risk (5-10%) Treat with laser from ora to anterior equator or most posterior pathology. Consider randomizing to cryotherapy

11. Choice of Intervention Peripheral Cryotherapy Peripheral Laser Photocoagulation Encircling Scleral Buckle Treatment of Pathologic PVD Monitoring

12. Questions for Physician Education 1Why is detection and counseling important ? 2What are the triggers for suspicion? 3What diagnostic complexity is posed by COL2A1:Exon2 disease: ocular predominant 4When and How is Stickler outcome improved ? 5What are diagnostic pearls ?

13. THE END (This power point was edited for the SIP Web Site)