1. 1 Enzymes

2. 2 What Are Enzymes? Proteins (Most enzymes are Proteins (tertiary and quaternary structures) CatalystAct as Catalyst to accelerates a reaction Not permanentlyNot permanently changed in the process

3. 3Enzymes catalyzeAre specific for what they will catalyze ReusableAre Reusable aseEnd in –ase-Sucrase-Lactase-Maltase

4. 4 How do enzymes Work? weakening bonds which lowers activation energy Enzymes work by weakening bonds which lowers activation energy

5. 5Enzymes Free Energy Progress of the reaction Reactants Products Free energy of activation Without Enzyme With Enzyme

6. 6 Enzyme-Substrate Complex substance enzyme substrate The substance (reactant) an enzyme acts on is the substrate Enzyme Substrate Joins

7. 7 Active Site region enzyme substrate bindsThe region of an enzyme molecule in which substrate binds. Enzyme Substrate Active Site

8. 8 Lock and Key Mechanism A theory that describes how only the correctly shaped substrate fits into a particular enzyme.

9. 9 Lock and Key Mechanism The enzyme is the lock. The substrate is the key.The substrate is the key. Enzyme Active Site substrate

10. 10 What Affects Enzyme Activity? Extreme Temperature are the most dangerous Extreme Temperature are the most dangerous - high temps denature (unfold) enzyme. - high temps may denature (unfold) the enzyme. Changes in pH (most like 6 - 8 pH near neutral) - Any variation from neutral may also denature the enzymes as well