Presentation on theme: "1 Enzymes. 2 What Are Enzymes? ProteinsMost enzymes are Proteins CatalystAct as Catalyst to accelerates a reaction Not permanentlyNot permanently changed."— Presentation transcript:
11 Temperature & pH High temperatures denature (Most like normal Body temperaturesHigh temperatures are the most dangerous reactions & denature enzymes (Most like normal Body temperatures) Most enzymes like near neutral pH (6 to 8) ionic saltsDenatured (unfolded) by ionic salts
12 Cofactors and Coenzymes Inorganic substances (zinc, iron) vitamins enzymatic activityInorganic substances (zinc, iron) and vitamins (respectively) are sometimes needed for proper enzymatic activity. Example :Example : Iron hemoglobin oxygen Iron must be present in the protein, hemoglobin in order for it to pick up oxygen.
13 Two examples of Enzyme Inhibitors a. Competitive inhibitors: resemble enzyme’s normal substrate competeactive site a. Competitive inhibitors: are chemicals that resemble an enzyme’s normal substrate and compete with it for the active site. Enzyme Competitive inhibitor Substrate
14Inhibitors b.Noncompetitive inhibitors: do not enter the active sitebind to another part enzymeenzyme change its shape alters the active site Inhibitors that do not enter the active site, but bind to another part of the enzyme causing the enzyme to change its shape, which in turn alters the active site. Enzyme active site altered Noncompetitive Inhibitor Substrate