1. Irrigated Tip Catheters for Radiofrequency Ablation in Ventricular Tachycardia Müssigbrodt, A., Grothoff, M., Dinov, B., Kosiuk, J., Richter, S., Sommer, P.,... & Hindricks, G. (2015). Irrigated Tip Catheters for Radiofrequency Ablation in Ventricular Tachycardia. BioMed Research International Volume 2015 (2015), Article ID 389294, 6 pages. Presenter ： Zhi-Fan Xu Adviser ： Dr.Yi-Chun Du Date : 2015/10/07 1

2. 生醫系統整合實驗室 Integrated Biomedical System Laboratory  Introduction  Materials and methods  Results  Conclusion Outline 2

3. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Introduction 3

4. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Feature Cardiac arrhythmia Cause of disease Hypoxia Myocarditis Congenital Heart Disease Symptom Chest Distress Angina Pectoris Ventricularfibrillation Ventricular Tachycardia (VT) 4 http://2014.igem.org/Team:ITESM-CEM/Project

5. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Drug treatment Abnormal liver function Digestive system damage Surgery High-risk Method of Treatment(1/3) 5 http://www.uho.com.tw/topic/ihealth/# http://www.psd100.com/ http://www.yxyx8.com/

6. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 6 Synchronized Cardioversion Myocardial Damage Scalded Skin Thromboembolic Pulmonary Edema & Heart Failure Method of Treatment(2/3) http://medical-dictionary.com/ http://www.herbalist.ru/.html

7. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 7 Method of Treatment(3/3) Catheter Ablation Direct current Ablation (1982)  Bundle of His Radiofrequency Ablation(1989) http://www.washingtonhra.com/

8. 生醫系統整合實驗室 Integrated Biomedical System Laboratory  Low Voltage  Electric Spark  General Anaesthesia  High Frequency Characteristics  Smaller Lesions & Coagulation Radiofrequency Ablation 8 http://www.xiangya.com.cn/

9. 生醫系統整合實驗室 Integrated Biomedical System Laboratory  Reduce damage of excessive heating  Reduce the formation of scabs and thrombosis Irrigated Catheter 9 http://www.dicardiology.com/

10. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Materials and methods 10

11. 生醫系統整合實驗室 Integrated Biomedical System Laboratory High frequency vibration Alternating current Role of Hot Evaporation of water & Dried 11 Principle of Radiofrequency

12. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Operating Procedures 12 http://www.gyclass.com/

13. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 13

14. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Frequency range of 100K to 200M Hz Power range of 20 to 30w Diameter range of 3 to 4mm(lesion) Bipolar & Unipolar Open-Loop & Closed-Loop System Specification 14

15. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Principle of Irrigated 15 https://www.bostonscientific.com/

16. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Closed-Loop & Open-Loop 16

17. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Results 17

18. 生醫系統整合實驗室 Integrated Biomedical System Laboratory VT Magnetic Resonance Imaging 18

19. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Importance of Catheter Contact Power transmission Temperature feedback 19

20. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Conclusion 20

21. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Decreases the likelihood of thrombus and char formation. Reconduction and the lack of effective transmural lesions play a major role for VT recurrences. To improve results and safety of catheter ablation. Conclusion(1/2) 21

22. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 22 Conclusion(2/2) Improvement of imaging integration technology. Using three-dimensionalcontact and noncontact mapping together with magnetic resonance imaging