1. How to Maintain a Healthy Liver R.T. Clement, MD Richard Clement Nutrition bewellhomeo@cs.com www.web-outpatients.com

2.  In a “healthy population” 40% of men and 20% of women have functional liver dysfunction.  Common liver function tests are misleading because most tests used in clinical practice measure hepato-cellular damage not function. Functional Liver Dysfunction

3.  Aminopyrine breath test assessing microsomal liver function  The galactose elimination test assessing the cytosolic liver function  The sorbitol clearance test assessing the liver plasma flow  The indocyanine green clearance test assesing the liver perfusion  The lidocaine Clearance test (Cytochrome P 450) But they are very rarely used Specific tests may be useful

4.  Bloating, slow digestion, constipation  Lack of energy  High Cholesterol and Triglycerides  Hormonal insufficiency  Intolerance to alcohol and/or medications  Recurrent infections Clinical Symptoms

5.  Many substances have an historical, anecdotal or well documented scientific data supporting their use.  Among the important substances  Milk thistle  Artichoke  Boldo  Curcumin  Alpha Lipoic Acid Maintenance of the liver

6.  Milk Thistle protect against genomic injury, increase hepatocyte protein synthesis, decrease the activity of tumor promoters.  (Am J Gastroenterology 1998 Feb; 93 (2) 139-43)  Milk Thistle is effective among patients with alcoholic cirrhosis  (J Hematology 1989 Jul 9 (1) 105-13) Milk Thistle (Silybum marianum)

7.  Boldo could decrease the metabolic activation of xenobiotics including chemical mutagens (Pharmazie 2001 Mar: 56(3): 242-3  Boldine has anti-inflammatory and antipyretic effects (Agents actions 1994 Oct; 42 (3-4) 114-7) Boldo

8.  Curcumin the yellow pigment in turmeric prevents malignancies (Cancer Epidemiology Biomarkers 2002 Jan 11 (1) 105-11).  Curcumin display antioxydative, anticarcinogenic and hypocholesterolemic activities. (J Nutrition 2001 Nov 131 (11) 2932)  Curcuminoids have lipid lowering potency. (J Nutrition 2001 Nov 131 (11) 2932) Curcumin

9.  Artichoke decrease hyperlipoproteinemia therefore prevents arteriosclerosis and coronary heart disease  (Arzneimittelforschung 2000 Mar; 50 (3): 260-5)  Artichoke extracts are safe and efficacious in hepato-biliary dysfunction and complaints (Wien Med Wochenschr 1999; 149 (8-10): 241-7) Artichoke

10.  Alpha lipoic acid is anti-hypertensive and diminish insulin resistance  (Hypertension 2000 Feb;39(2) 303-7) Alpha Lipoic Acid

11.  Liver detox  Fatty liver  Secondary liver toxicity of alcohol, drugs and/or medications  As an adjunct to standard therapies in Hepatitis  As part of a Diet program in Obesity Indications

12.  One capsule at each meal with food  Duration of supplementation one month or more according to the condition. Posology: Hepatika V 5

13. Side-effects and Adverse Reactions Non recorded after one year of distribution 3/2002 to 11/2012

14. Clinical Cases Hepatitis C “cured” Patient from Los Angeles Fatigue Depression (suicidal) Viral load 175.000.0000 Bed Rest, diet Hepatika 5 for 2 months One Year Later Clinical improvement Viral load undetectable

15. Clinical Cases Hepatitis C Male Florida Treated by Chinese Herbs and Thymus Extract Diminution of the Virus Load after the Hepatika 5 was added to the treatment.

16.  1-877-438-3042 / 305-594-2145  Or fax your order at 305-594-2174  Email: bewellhomeo@cs.combewellhomeo@cs.com  www.web-outpatients.com How to order: Hepatika V 5