1. Liver Detox Complex

2. Product Design A combination of ingredients designed to support liver health and detoxification Contains significant amount of Milk Thistle Seed extract (350 mg per serving) Contains plant-based, liver-specific products such as Burdock root, Aloe vera, Fennel seed and Artichoke leaf, plus L-methionine Can be used in place of lower dose stand-alone Milk Thistle product, since it provides added detoxification benefits

3. Importance of a Healthy Liver The liver is the bodys refinery Absorbs, metabolizes, and neutralizes environmental pollutants, toxins, and nutrients Stores carbohydrates and manages fat, protein and carbohydrate metabolism.

4. Insults to the Liver Drugs / Medications Require the liver to metabolize these in addition to foods metabolized from dietary intake (including alcohol) Chronic drug consumption taxes the liver Pollutants and other Environmental Toxins Require the liver to metabolize these in addition to foods metabolized from dietary intake Consumption of fish from waters polluted with heavy metals, PCBs and others add to the livers duty to purify and break down these substances in the body.

5. Milk Thistle Seed extract Silybum marianum Herb native to the Mediterranean Silymarin Repairs liver cells damaged from drug or alcohol ingestion Prevents other liver cells from damage by blocking toxins at the membrane level Functions as an antioxidant May contain anti-inflammatory activity Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects. Summary, Evidence Report/Technology Assessment: Number 21, September 2000. Agency for Healthcare Research and Quality, Rockville, MD

6. Burdock Root Common weed traditionally used for cleansing functions Naturally contains plant sterols, oils, and tannins. Research shows a clear dose-dependant effect of burdock extract on liver enzymes in animals. Abnormal liver histology was also reduced, likely due to its antioxidant properties. Physicians Desk Reference for Herbal Medicines, 2004.

7. L-Methionine Sulfur-containing essential amino acid Precursor for SAMe, L-cysteine, glutathione, taurine and sulfate as well as protein synthesis Possesses antioxidant abilities May reduce the liver-toxic effects of hepatotoxins

8. Why is SAMe important? SAMe = S-adenosyl-L-methionine Natural substance in the cells Used in Europe as a drug to treat liver disorders, depression, osteoarthritis and fibromyalgia Levels are depleted in liver disease Promotes fluidity of liver lipid membranes In studies, SAMe: improved LFTs (Liver Function Tests), increased hepatic glutathione levels, restored normal hepatic function in cholestasis patients and prevented or reversed hepatoxicity induced by drugs, alcohol and various chemicals

9. How often should I take it? Suggested use: Take 1 or 2 capsules a day with a glass of water, between meals Can be taken in place of a lower dose stand-alone Milk Thistle Seed extract product Important to maintain a healthy diet, exercise and reduce stress levels in conjunction with dietary supplementation

10. Liver Detox Complex High amounts of Milk Thistle Seed extract (350 mg per serving) Provides natural sources of antioxidants Contains the essential amino acid L- methioninea precursor for SAMe synthesis Vegan / vegetarian 60 and 120 counts