1. Modeling Genetic Inheritance Carolina Inquiries in Science 25-1006 $159.95

2. Kit Contents 16 spinners IDA’Clipieces (three large containers with a variety of colored pieces and connectors) Teacher’s manual and reproducible Student Guide

3. Student Learning Goals Observe the inheritance of traits over generations Recognize contrasting phenotypes Propose and test models for inheritance of phenotypes Make predictions about inheritance of phenotypes

4. Prior Knowledge This kit will work best as a reinforcement to basic Mendelian Genetics. Students should have a working knowledge of the following terms: alleles, dihybrid, dominant, genes, genotype, heterozygous, homozygous, hybrid, monohybrid, phenotype, Punnett squares, recessive, traits,P 1 - maternal parent, P 2 - paternal parent F 1,-first generation F 2,-second generation

5. Students should be able to write genotype and phenotype abbreviations and have some knowledge as to how Punnett squares work.

6. How the Lab works Step 1: Students are given a variety of IDA’Clip pieces and are asked to build an organism, real or imaginary, whose inherited traits can be easily observed and studied. It is suggested that you limit the number of pieces you give the students to cut down on the amount of time this step takes.

7. Step 2: the class will then look at the organisms built and choose the ‘species’ everyone will build. Step 3: as a class, compile a list of 4-6 traits on which to focus. Determine which form of each trait is dominant and which form is recessive. Assign letters to represent each allele. Step 4: create a data table listing the names of the traits, the dominant and recessive phenotypes and dominant and recessive genotypes for the traits.

8. Once you know what organism you are studying A group of four will split into two pairs. One pair will create the P1 (female organism) and the other will create the P2 (male organism) The spinners will be used to go through the traits and figure out what your parental organisms will look like. List the genotype and phenotype for each trait and reassemble as a group of 4 to compare the parents.

9. F1 Generation The group of four will create a Punnett square using their parental (P1-P2) organisms. Number each of the boxes squares 1-4 and use the spinners to determine each trait in the F1 generation. Create your organism from the genotypes and phenotypes you spun.

10. F2 generation Join with members of another group and cross your F1 organisms to create a member of the F2 generation. Determine the genotypes and phenotypes of the F2 generation using punnett squares and the spinner like you did for the F1 generation. Use remaining materials to create your F2 organisms.

11. Finish Up Using the chart in the student guide, put an X in the appropriate column for each of your organisms. As a class compile a list of the rate of occurrence for each trait and graph the results. Complete the questions at the end of the guide.

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