1. DNA nanotechnology: Geometric sorting boards
David W. Grainger
Nature Nanotechnology 4, (2009)
Speaker：Zong-Han Li
Instructor: Kun-Mao Chao
2012/6/4

2. Outline Geometrical self-assembly DNA Origami
Surface patterning with DNA tiles
DNA tiny chips
Geometrical self-assembly
2012/6/4

3. DNA Origami A: single-stranded DNA and staple strands.
B: Design of a self- assembled DNA origami structure and geometry of the incorporated double-stranded DNAs.
Endo, M. and Sugiyama, H
Recent Progress in DNA Origami Technology.
Current Protocols in Nucleic Acid Chemistry. 45:12.8.1–
2012/6/4

4. Surface patterning with DNA tiles.
a:Nanoscale DNA tiles
b:DNA tiles decorated with different functional reagents are used to create a variety of functional devices from a mixed solution of tiles.
David W. Grainger
Nature Nanotechnology 4, (2009)
doi: /nnano
2012/6/4

5. DNA tiny chips 6nm DNA Origami for Faster, Smaller Computer Chips
R. J. Kershner et al
Nature Nanotechnology 4, (2009) 
6nm
DNA Origami for Faster, Smaller Computer Chips
IBM suggests that it could take up to
10 years to test and refine the process
for manufacturing.
Tiny, triangular DNA structures self-assemble on silicon.
Credit: IBM
2012/6/4

6. Geometrical self-assembly
Attractive interactions between DNA origami tiles are coded in their complementary shaped edges, recapitulating the binding of complementary sequences of bases to form a DNA double helix.
DNA nanotechnology: Geometrical self-assembly
Andrew J. Turberfield
Nature Chemistry 3, 580–581 (2011) doi: /nchem.1097
2012/6/4

7. Thanks for your attention
2012/6/4