1. By Abhi Gollapudi and Matt Pruss
Marfan’s Syndrome
By Abhi Gollapudi and Matt Pruss

2. What is it
Marfan's Syndrome is a disorder of the connective tissue, the tissue that strengthens the body’s structures.
A despise that is characterized by elongated bones (especially of the limbs and digits) and abnormalities of the eyes and circulatory system.

3. Symptoms
People with Marfan's Syndrome are usually tall with long, thin arms and legs and spiderlike fingers. Then they stretch their arms and are usually longer then their height.

4. Symptoms Cont.
A chest that sinks in or sticks out- funnel chest or pigeon breast.
Flat feet
High arched palate and crowded teeth
Hypotonia
Joints that are to flexible
Learning disabilities
Movement of the lens of the eye fro its normal position (dislocation)
Nearsightedness
Small lower jaw
Spine that curves to one side (Scoliosis)
Thin narrow face
It is estimated that 1 in 5,000 people in the United States have this disorder

5. Treatment Vision problems can be treated when possible
Take care of scoliosis when possible
Medicine to slow the heart rate helps prevent stress on the Aorta
Avoid participating in contact sports, and surgery may be needed to replace aortic root and valve
Before dental appointments, people with Marfan's Syndrome have to take medicine to be safe from Endocarditis
Pregnant woman must also be carefully monitored because of the huge amounts of stress on their heart.

6. How It’s Inherited
Marfan's syndrome is caused by a defect in the Filrillin-1 gene. The Filrillin-1 gene is the building block for elastic tissue in the body.
Marfan's syndrome is inherited which means it is passes down through the families.
A person has a 50% chance in inheriting the disease if a family member is diagnosed with it.
However up to 30% of cases have no family history. Such cases are called “sporadic”. In sporadic cases, it effects everyone in different ways.

7. Bibliography
Englert, Chad Chad Haldeman. "Marfan Syndrome - PubMed Health." Pubmed Health. 10 May Web. 02 June <