1. IPL Intense Pulsed Light System by Steinbeis Transfercentre Biomedical Engineering, Donaueschingen, Germany Director: Prof. Dr. Bernhard Vondenbusch

2. Pulsed Light Systems target the Global Anti-Aging Market  Systems using high energy pulses of light (generated by laser or flshlamp) are used in the field of medical wellness, the beauty / aesthetic area and cosmetic dermatology with typical application in:  Removal of unwanted hair,  Removal of coloration changes,  Treatment of telangiectasis,  Treatment of acne  Skin rejuvenation  Large amount of clinical studies show the effectiveness of the method, especially in the removal of unwanted hair.  Photorejuvenation currently ranks as one of the highest volume aesthetic procedures in the world.  Today, the Intense Pulsed Light (IPL) technology, which uses high energy flashlamps as sources of light, has replaced the laser devices in many applications.

3. IPL Devices  Analysis of the market shows, that only a few devices reach the current state of the art  Main disadvantages of current devices are  Approval as medical device missing  Poor usability of the main system  Change of the flashlamp too complicated  Poor usability of the handheld applicator  High level of pain for the patient  High costs for the customer Competitor´s device, showing the main system and the handpieces, which are applied to the patient to deliver the light pulses

4. Photoepilation: Removal of Hairs 532 nm 810 nm 595 nm 694 nm High energy light pulses applied to the skin heat up the root of the hair (absorption of energy in coloured hair) – the hair generating cells are destroyed. The optimum wavelenght of light is between 650 nm – 1200 nm. High densities of energy are required: 10 J/cm 2 to 45 J/cm 2. Problem: The upper layers of the skin must not be heated!

5. Clinical Studies (success rate in removal of hairs using IPL devices) Author / year n No. Of treatments reduction Marayiamis 2003 1571 53 % Stangl 2003 2003115 90 % Bjerring2006313 56 % Troilius1999204 80 % Sadick1999343,9 83 % Schröter199940677%

6. High voltage supply, storage of energy User interface, sensors, alarms Cooling system for filter and flashlamp (de-ionized water) Control of electric pulses 400 V / 400 Amps Main system Applicator Flashlamp, filter, sensors, waveguide; HoseIPL-TechnologySpotsize 50 mm x 12 mm Pulses 1 Pulse / second Pulseduration 5 – 30 ms Wavelength 650 – 1200 nm

7. Control of light pulses Temperatures in hair / skin using electronic pulse control: pulse control keeps skin temperature below damage level Sub-Pulse 5 – 10 ms Interval 5 – 20 ms Temperature Time Temperature hairroot, to be destroyed Temperature skin, not to be damaged Damage level No. of sub-pulses: 1 – 9, according to required amount of energy

8. IPL-Prototype, developed at STC (showing main system and hand piece)

9. The STC IPL-Prototype  Prototype includes state-of-the-art technology  Know How of IPL technology is available at STC Biomedical Engineering: Usability study, design study, patent and literature reviews, own calculations and circuit designs, control software, results and experience from own measurements, list of components and distributors, list of competitors  German patent granted in 2010  Complete Know How including the prototype can be transferred to SME partners in India.