1. Every eukaryotic cell needs oxygen. So the big question is...

2. Small Organisms (single or few cells) Single-celled organisms can simply absorb Oxygen from the environment through diffusion No circulatory or pulmonary system needed Just a large surface area that is moist is all that is needed.

3. Complex Water Organisms Water is a more efficient exchange medium for Oxygen (than air) But Water has a lower percentage of Oxygen dissolved in it (than air) Gills develop to maximize surface area –Constant circulation of water –Water is difficult to move Bulk Flow now necessary

5. Complex Land Animals Air is a less efficient means of absorbing Oxygen than water Air has a higher percent of Oxygen than water Lungs evolve to maximize surface area –S.A. of tennis court –Intercostal/diaphragm muscles allow periodic exchange Bulk Flow also necessary

6. The 4 steps of Respiration in Mammals 1. Air or water, containing oxygen, is moved past a respiratory surface by bulk flow. 2. O 2 and CO 2 are exchanged through the respiratory surface by diffusion. O 2 enters the capillaries and CO 2 is removed. 3. Gases are transported between the respiratory system & the tissues by the bulk flow of blood (pumped by the heart) 4.Gas exchange between tissue and circulatory system. O 2 diffuses out of capillaries and CO 2 diffuses into them. Diffusion = movement of particles from a region of high concentration to one of low concentration. Bulk flow =movement of many particles from an area of higher pressure to one of lower pressure

8. Diffusion of O 2 and CO 2 When a cell carrying O 2 nears another cell that is lacking in O 2, diffusion will occur When a cell is lacking in O 2 and nears an O 2 rich region, diffusion will occur The same process happens with CO 2

9. Summary of diffusion in the lungs and tissue

10. The next question is... So now we understand how this diffusion works between neighboring cells

11. A liquid conduit containing the liquid “blood” This Bulk Flow is necessary to bring O 2 to every cell in the body Also necessary to protect and upkeep cells The liquid that is circulated around has a number of components... Transporting O 2 and other stuff (The Circulatory System)

12. The Components of Blood Red Blood Cells: –Transport O2 White Blood Cells: –Protect the cells from infection/invasion Platelets: –Clot the blood to prevent it from spilling out when a rupture of the fluid conduit occurs Plasma: –Glucose, hormones, etc. suspended in a viscous goo

13. Functions of Blood 1. Transportation:Blood transports oxygen, carbon dioxide, nutrients, hormones, heat, and wastes. 2. Regulation: Blood helps regulate pH, body temperature, and water content of cells. 3. Protection:Protects against blood loss through clotting, and against foreign microbes and toxins through the activities of phagocytic white blood cells and plasma proteins.

14. Red Blood Cells Have a protein called “Hemoglobin” which binds to O 2 Binds to CO much more strongly Contain no nucleus! Recycled every week or so Biconcave shape

15. Oxygen atoms bond to the heme Each can hold 4 o

16. White Blood Cells Slip in between cells Recognize and destroy foreign matter

17. Platelets Aid in blood clotting Recognize micro tears in blood conduits and bind together to form a clot

18. How blood is transported Arteries: –Structures that carry blood away from the heart –Rigid to take pressure of blood right out of heart Veins: –Looser to expand more –Store great quantities of blood Capillaries: –Very narrow tubes between arteries and veins where diffusion occurs

19. How Blood Flows: The Heart

20. The Heart Contraction of ventricles –Larger of heart chambers –Takes blood in from the atria –Pumps blood out to the body Contraction of atria –Smaller chambers –Takes blood in from body –Pumps blood into the ventricles Coordinated beating of one then the other