1. Maryam Treifi Dr. Mircea Muresan Faculty of Medicine, UMPh Targu Mureș Department of Surgery Targu Mures County Hospital

2. IBD involves inflammation or ulceration in all or part of the digestive tract. Two major forms of IBD are recognised: Crohn’s disease (CD), which can affect any part of the GI tract Ulcerative colitis (UC), which affects only the colon Chronic inflammation impairs the ability of the affected organs to function properly, leading to symptoms such as abdominal cramping, alteration of bowel habits, rectal bleeding and fatigue. IBD can be debilitating and can sometimes lead to life-threatening complications.

4. The aim of the retrospective study was to analyse how many cases of IBD complications had ended up in surgery and the type of procedure that was undertaken for each of two main diseases.

5. The retrospective study was conducted on records of patients hospitalised after being operated on at the Surgery department of the County Hospital in Târgu Mureş between the years 2009-2015 to date. The following factors were taken into consideration: age, sex, histopathology and the type of procedure carried out. Data was collected and put into tables and charts using Microsoft Excel program.

6.  Although both conditions have a worldwide distribution, the highest incidence rates and prevalence have been reported from northern Europe, the UK and North America. Both race and ethnic origin affect the incidence and prevalence of Crohn’s Disease and Ulcerative Colitis.  Approximately 25% patients are diagnosed before their 25 th birthday and there is increasing evidence that disease commencing in youth is more extensive and more aggressive than that occurring in older patients.

7.  Exact cause is unknown  Genetic factors  Immunological  Microbial  Psychosocial

8. Crohn’s Disease  Failure of medical therapy, with acute or chronic symptoms producing ill-health  Complications (e.g. Toxic dilatation, obstruction, perforation, abscesses, enterocutanous fistula)  Failure to grow despite medical treatment  Presence of perianal sepsis Ulcerative Colitis  Failure of medical treatment  Toxic dilatation  Haemorrhage  Dysplasia  Imminent perforation

11. During the studied period, of the 25 diagnosed patients, 21 had complications due to Ulcerative Colitis while 4 were due to Crohn’s. The most affected age group was the 51-60, with a female predominant ratio of 1:0.19. The most common procedure for Ulcerative Colitis were the enterectomies (50%) when in comparison to other procedures. In Crohn’s disease, the most common procedure undertaken was the right hemicolectomy (43%).

15. Life with IBD can be challenging, however, it should not impede ones ability to live a normal life. Patients with IBD can go to college, hold a normal job, get married, have children etc. As is the nature of any chronic, unpredictable disease, there will be ups and downs. The progress made in IBD research and treatment is astounding and will only improve in the years to come.

16. Books  Kumar and Clark. Clinical Medicine, eighth edition 2012  Longmore, Wilkinson, Davidson and Mafi. Oxford Handbook of Clinical Medicine, eight edition 2010 Websites  Surgery for Crohn’s Disease and Ulcerative Colitis, August 31 st 2010, www.ccfa.org  www. emedicine.medscape.com  Centres for disease control and prevention, www.cdc.gov/ibd

17. THANK YOU