1. Nano-Biomimetics Team Г

2. Nano-biomimetics? What is nano-biomimetics? What is nano-biomimetics? Biological self-assembly Biological self-assembly Viral assembly Viral assembly Gecko Feet Gecko Feet

3. What is nano-biomimetics? Utilizes biological mechanisms to create materials Utilizes biological mechanisms to create materials Mimicking biological self-assembly processes Mimicking biological self-assembly processes Using single biological units as a building block along with inorganic materials Using single biological units as a building block along with inorganic materials Mimics biology at the molecular level Mimics biology at the molecular level Synthesizing structures that mimic biological structures Synthesizing structures that mimic biological structures

4. Utilizing biological mechanisms Atom-precise manipulation yields composite materials and nano-scale structures with desirable properties Atom-precise manipulation yields composite materials and nano-scale structures with desirable properties Parallel self-assembly processes achieve precision with high speed and reproducibility Parallel self-assembly processes achieve precision with high speed and reproducibility

5. Biological self-assembly Bottom-up fabrication process Bottom-up fabrication process Continuing miniaturization of devices in nanotechnology Continuing miniaturization of devices in nanotechnology Nature already assembles its smallest components into ordered structures Nature already assembles its smallest components into ordered structures

6. Biological self-assembly: applications Genetically Engineered Proteins for Inorganics (GEPIs) Genetically Engineered Proteins for Inorganics (GEPIs) Methods Methods Biopatterning Biopatterning Neuron growth on patterned substrates Neuron growth on patterned substrates

7. Biological self-assembly: applications

8. Viral assembly: biology Abalone shell mostly chalk, but 3000x stronger because of crystal structure Abalone shell mostly chalk, but 3000x stronger because of crystal structure Very difficult to assemble crystals, requires precise control in 3-D Very difficult to assemble crystals, requires precise control in 3-D

9. Viral assembly: biomimetic Genetically engineered virus attaches to molecule of building material Genetically engineered virus attaches to molecule of building material Viruses orient themselves in solution, producing well-ordered liquid crystal Viruses orient themselves in solution, producing well-ordered liquid crystal

10. Viral assembly: applications Procedure can easily scale up Procedure can easily scale up Multiple applications Multiple applications Better materials Better materials

11. Mimicking biological structures Top-down approach using lithography, scanning probes, CVD, sputter coating, and many other techniques normally unassociated with biology Top-down approach using lithography, scanning probes, CVD, sputter coating, and many other techniques normally unassociated with biology Requires very precise manipulation Requires very precise manipulation

12. Gecko feet: biology Millions of hairs called setae Millions of hairs called setae Fiber radius is nanometer-scale Fiber radius is nanometer-scale Adhesion due to van der Waals and capillary forces Adhesion due to van der Waals and capillary forces

13. Gecko feet: biomimetic Use electron beam lithography and dry etching to create synthetic polymer hairs Use electron beam lithography and dry etching to create synthetic polymer hairs Attach to flexible base Attach to flexible base Palm-sized piece can support a human Palm-sized piece can support a human

14. Gecko feet: applications

15. Nano-biomimetics! Create materials with novel properties Create materials with novel properties Synthesize existing bio-materials in larger quantities Synthesize existing bio-materials in larger quantities Integrate biomolecules and materials with inorganic ones for hybrid systems Integrate biomolecules and materials with inorganic ones for hybrid systems

16. References Bio-assembly Bio-assembly Sarikaya, Mehmet. "Moleucular biomimetics: nanotechnology through biology.“ Nature Materials Sept. 2003. Sarikaya, Mehmet. "Moleucular biomimetics: nanotechnology through biology.“ Nature Materials Sept. 2003. Gyorvary, Erika S. "Biomimetic Nannostructure Fabrication: Nanolithographic Lateral Patterning and Self-Assembly of Functional Bacterial S-Layers at Silicon Supports." 11 Dec. 2002. Nano Letters. Vol. 3. 2004. 315+ Gyorvary, Erika S. "Biomimetic Nannostructure Fabrication: Nanolithographic Lateral Patterning and Self-Assembly of Functional Bacterial S-Layers at Silicon Supports." 11 Dec. 2002. Nano Letters. Vol. 3. 2004. 315+ Zhang, Shuguang. "Fabrication of novel biomaterials through molecular self-assembly." Nature biotechnology Oct. 2003. Zhang, Shuguang. "Fabrication of novel biomaterials through molecular self-assembly." Nature biotechnology Oct. 2003. Quinion, Michael. "Turns of Phrase: Biomimetics." World Wide Words. 22 Nov. 1997.. Quinion, Michael. "Turns of Phrase: Biomimetics." World Wide Words. 22 Nov. 1997.. Viral Assembly: Viral Assembly: http://www.sunlandimports.com http://www.sunlandimports.com http://www.sciencemag.org/cgi/content/full/296/5569/892 http://www.sciencemag.org/cgi/content/full/296/5569/892 http://www.pnas.org/cgi/content/full/100/12/6946 http://www.pnas.org/cgi/content/full/100/12/6946 http://web.mit.edu/giving/spectrum/fall05/building_on_nature.html http://web.mit.edu/giving/spectrum/fall05/building_on_nature.html http://pubs.acs.org/cgi-bin/sample.cgi/nalefd/2004/4/i01/html/nl0347536.html http://pubs.acs.org/cgi-bin/sample.cgi/nalefd/2004/4/i01/html/nl0347536.html Gecko foot: Gecko foot: http://www.andrew.cmu.edu/user/gshah/Project_modeling.htm http://www.andrew.cmu.edu/user/gshah/Project_modeling.htm http://photos.wildmadagascar.org/images/uroplatus_fimbriatus-0143.shtml http://photos.wildmadagascar.org/images/uroplatus_fimbriatus-0143.shtml http://www.houstonvoice.com/2004/6-18/view/actionalert/action.cfm http://www.houstonvoice.com/2004/6-18/view/actionalert/action.cfm http://onnes.ph.man.ac.uk/nano/Publications/Naturemat_2003.pdf http://onnes.ph.man.ac.uk/nano/Publications/Naturemat_2003.pdf Spiderman: http://spiderman.sonypictures.com Spiderman: http://spiderman.sonypictures.com