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Jeremy Leibfried Tyler Gronli

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1 Jeremy Leibfried Tyler Gronli
Fasciola hepatica Jeremy Leibfried Tyler Gronli

2 Introduction Phylum: Platyhelminthes Flat worm Liver fluke
Effects sheep, cattle, and sometimes humans Tyler

3 Tyler

4 Interesting Facts Eggs found in mummies
1st fluke or trematode to be reported 1379 Reported in Publication (Le Bon Berger) 1st discovered in sheep Tyler

5 F. hepatica Definitive host: Intermediate host Geographic Range Sheep
Cattle Humans (Accidental) Other Mammals Intermediate host Fresh Water Snail Geographic Range Cosmopolitan; anywhere sheep and cattle are raised Tyler

6 Morphology Adult fluke Flat leaf like body 20-30mm long 8-15mm wide
Tyler

7 Site of Infection Ingestion Metacercariae Ex-cyst in Duodenum
Burrows through Intestinal Wall Enters Peritoneal Cavity Migrates to Liver Jeremy

8 Jeremy

9 Miracidia Egg Jeremy Cercariae Metacercariae

10 Symptoms Abdominal Pain Anemia Hepatic Tenderness
Hepatomegaly resulting from Edema Intermittent Fever Jaundice Lethargy Nausea Prolonged High Fever Secondary Infections Vomitting Tyler

11 Symptoms Acute Chronic Halzoun More common in sheep
10,000+ Metacercariea consumed at one time Dramatic Liver Inflamation, Frequently Resulting in Death Chronic More Common and Rarely Fatal Nonspecific Symptoms Halzoun Eating raw, infected liver Infects pharynx Causes swelling and obstructs breathing Tyler

12 Diagnosis Stool Samples Duodenal or Biliary Aspirate Antibody Test
Yellow-Brown Eggs Eggs Don’t Show for 4 Months Duodenal or Biliary Aspirate Antibody Test Can detect 2 Weeks After Infection Ultrasound Visualize Adults in Bile Duct CT Scan Reveals Burrows in Liver Jeremy

13 Treatment Bithional Triclabendazole Surgery Highly Effective
Large Dose High Cost Long Treatment Period Triclabendazole Easier to Use 1-2 Oral Doses in 24 hrs Virtually 100% Effective Surgery Jeremy

14 Control Methods Eduaction Moluskicide
Cheapest and Most Cost Effective Way Wash Aquatic Vegetables in 6% Vinegar for 5-10 minutes Better herding practices Keep herds away from aquatic areas Moluskicide Controls Intermediate Snail Host Jeremy

15 Jeremy


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