Presentation on theme: "Disadvantages of Lactic Acid in Human Performance"— Presentation transcript:
1Disadvantages of Lactic Acid in Human Performance Disadvantages of lactic acid in human performance – counterpoint article Lamb 2006; Robergs 2004; Bangsbo 1996.
2Increase abundance of H+ ions can change the pH level. Lactate is produced as a result of ATP formation via non oxidative energy system – glycolysisIncreased lactate concentrations in the blood have been observed, resulted in decreased athletic performanceIncrease abundance of H+ ions can change the pH level.Negative effects of lactic acid could be multi- factorialWith high intensity exercise, immediate and non oxidative energy systems are used to produce energy (ATP).Studies have shown that as lactate levels increase in the blood as a result of high intensity exercise, performance levels have been observed to decreaseThe utilization of glucose via glycolysis can cause a change in the pH due to an increase abundance of H+ in the muscle cellChanges in pH levels and the accumulation of lactate could be multifactorial leading to acidosis and decreased athletic performance
3Graph – open circles represent control group performing exercise to point of exhaustion with no lactate build up in bloodDarkened circles represent exhaustion point when lactate already present in blood via UE exercise and subjects were asked to perform a LE leg extension exerciseY axis on left – represents blood lactate levelsY axis on right side – muscle pH. Notice that as muscle pH level decrease as of lactate formation in blood, the potential for exhaustion is sooner.
4H+ could depress Ca 2+ activation of actin myofilaments Increased levels of lactate and H+ ions could impair SR Ca 2+ release channelsH+ could depress Ca 2+ activation of actin myofilamentsH+ induces a reduction of the Ca 2+ reloading into the SRStudies have shown that the handling of intracellular Ca2+, through increases in lactate levels and H+ions may induce an impairment to the SR Ca2+ release channelsThis may have an effect of the actin myofilament during muscle contractionH+ions could reduce the amount of Ca2+ that is available for reloading in the SR
5Additional controversies: Difficulty in extrapolating the results to in vivo conditions – exercise performance in humansStudies based on isolated, non contracting muscle and skinned muscle fibers resulting in artificial non exercise related conditionsPositive correlation between transport capacity and performance, suggesting that lactic acid accumulation is a disadvantage.Although high levels of lactic acid & low pH are not primary cause of fatigue, it appears to contribute to fatigue during intense exerciseStudies were mainly conducted on animals hard to infer results to humans.Experiments conducted on resting muscle of animalsPositive correlation btwn transport capacity and lactic acid accumulation. (higher LA, less capacity to transport)Although high LA & low pH levels are not the primary cause of fatigue in humans, it appears that it contributes to fatigue particularly when performing intense exercise.