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Aujeszky-disease.

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Presentation on theme: "Aujeszky-disease."— Presentation transcript:

1 Aujeszky-disease

2 Aujeszky’s disease, also known as pseudorabies, is caused by an alphaherpesvirus that infects the central nervous system and other organs, such as the respiratory tract, in a variety of mammals except humans and the tailless apes. It is associated primarily with pigs, the natural host, which remain latently infected following clinical recovery (except piglets under 2 weeks old, which die from encephalitis).

3 A diagnosis of Aujeszky’s disease is established by detecting the agent (virus isolation, polymerase chain reaction ), as well as by detecting a serological response in the live animal.

4 Alpha-herpesvirus gene-deleted vaccine: prohibited in Hungary from 2006 test: gB/gE ELISA neurological signs, respiratory signs, abortion chronic symptomless carriers eradication program treatment of meat

5 free pig: virus, antigen or DNA is not detected gB-ELISA – kept in free herd

6 infected pig: clinical signs, pathological lesions + epidemiological link virus, antigen or DNA detection gB-ELISA +

7 suspected of being infected pig:
suspicious clinical signs, , pathological lesions presence of virus, antigen or DNA is not excluded contact with infected animal within 40 days or inseminated with infected semen

8 free herd: no infection for 2 years
epidemiological conditions (e.g. isolation, controlled movements, laboratory examinations, records) (!!!) no vaccination testing of all breeding sows and boars and representative sample of fattening pigs insemination or natural breeding with negative semen/boars

9 free herd with vaccination:
no infection for 2 years (until 2006) only gE gene-deleted vaccine epidemiological conditions (e.g. isolation, controlled movements, laboratory examinations, records) testing of all breeding sows and boars and representative sample of fattening pigs with gE-ELISA insemination or natural breeding with negative semen/boars

10 infected herd: confirmed disease or infection movement restrictions
elimination of the herd until the end of production period (max. 7 months) state compensation

11 control of free status: regular tests
large scale holding: all boars: every 6 months sows: 20-50% every 6 months representative sample of fattening pigs small holding: all boars and sows: every year 5% of pigs over 4 months artificial insemination centre: test every 6 months

12 If positive or inconclusive:
free status is suspended official surveillance suspicious clinical signs, , pathological lesions: sample to the veterinary institute

13 repeated test in 14 days with gB-ELISA and VN
negative: restoration of free status positive or inconclusive: killing, sample to the veterinary institute + all breeding animals over 6 months are tested virus, antigen or DNA is not detected from the killed animal + all test is negative: restoration of free status virus, antigen or DNA is detected from the killed animal or there is positive test: elimination of the infected herd

14 If epidemiological conditions (e. g
If epidemiological conditions (e.g. isolation, controlled movements, laboratory examinations, records) are not complied with: suspension of free status + control serological tests

15 wild boar: individual negative gB-ELISA test for breeding or further keeping
disease in other species: notification


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