1. LIPIDS Part II: Digestion, Absorption, Transportation & Metabolism

2. Digestion of Triglycerides Goal: Triglyceride >>> monoglycerides glycerol fatty acids

3. Digestion Salivary glands Large intestine Small intestine Common bile duct Pancreas Pancreatic duct Stomach Mouth Gallbladder Sublingual salivary gland Tongue Liver Large intestine Small intestine bile lipases

4. Absorption two different routes small bits bloodstream glycerol, short fatty acids larger bits lymph monoglycerides, long fatty acids

5. Four Types  Chylomicrons  VLDL  LDL  HDL protein phospholipid cholesterol triglyceride Lipoproteins = Fat Transporters

6. HDL VLDL LDL Chylomicron Types of Lipoproteins

7. LipoproteinPrimary Ingredient FunctionBlood Test Chylomicrons TriglycerideTransports fats (from intestines) to cells “ triglycerides ” VLDL TriglycerideTransports fats (from liver) to cells “ triglycerides ” LDL [recycled VLDLs] CholesterolTransports cholesterol to tissues “ bad cholesterol ” HDL ProteinTransports cholesterol to liver “ good cholesterol ” Lipoproteins Compared

8. Fat Metabolism Triglycerides Energy Adipose Lipoprotein Lipase (LPL) Adipose Hormone-sensitive Lipase

9. LIPIDS Part III: Lipids and Health

10. Function of Fats  Energy [adipose tissue]  Insulation  Protects bones and organs  Essential Fatty Acids  Linoleic (omega-6)  Linolenic (omega-3) Eicosanoids

11. Heart Disease: Blood Lipid Profile  Total Cholesterol  LDL & HDL  Triglycerides

12. Heart Disease & Fatty Acids High LDLs  Saturated  Trans Low HDLs  Trans  Omega-6s Low LDLs  Monounsaturated  Omega-3s High HDLs  Omega-3s AVOIDEMPHASIZE

13. Cancer & Fat  Total Fat  Excess Calories  Animal Fats  Types of Fatty Acids  Lack of Vegetables & Fruits and other plant foods PHYTOCHEMICALS