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V D Latent Dorsalizing Factors The Point of Fertilization Orients the D/V Axis of the Frog.

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Presentation on theme: "V D Latent Dorsalizing Factors The Point of Fertilization Orients the D/V Axis of the Frog."— Presentation transcript:

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2 V D Latent Dorsalizing Factors The Point of Fertilization Orients the D/V Axis of the Frog

3 ß-Catenin Acts as a Morphogen to Pattern the D/V Axis

4 Gastrulation: From Embryo to Tadpole

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6 Cleavage: From Fertilized Egg to Blastula

7 Gastrulation of A Frog Embryo

8 Evolutionary Conservation of Hox Expression Patterns

9 Evolutionary Conservation of Hox Gene Function

10 Wild-Type Antenna Antenna Transformed by Mouse Hox Gene Wild-Type Leg Claw

11 Neural Induction by the Spemann Organizer

12 The Mangold Spemann Experiment

13 Chordin Versus BMP Expression in Frog Embryo

14 Allow Cells to Differentiate Animal Caps Reaggregate Cells Incubate Dissociate Cells

15 Allow Cells to Differentiate Animal Caps Reaggregate Cells Incubate Dissociate Cells + BMP4 + Chordin Allow Cells to Differentiate Animal Caps Reaggregate Cells Incubate Dissociate Cells + BMP4

16 Allow Cells to Differentiate Animal Caps Reaggregate Cells Incubate Dissociate Cells + BMP4 + Chordin Allow Cells to Differentiate Animal Caps Reaggregate Cells Dissociate Cells Incubate + BMP4 + Chordin

17 Evolutionary Conservation of BMP Signaling

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19 Inverted-brate Hypothesis Evolutionary Conservation of Neural Induction


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