2. Circulatory System Chapter 14, 15, 16

3. The Heart’s Layers Endocardium – innermost layer, squamous layer Myocardium – thick middle layer, cardiac muscle Pericardium – outermost layer

4. Heart Anatomy – Blood Flow

6. HeartbeatHeartbeat AnimationAnimation Lub – Dub – Contraction of Ventricles– systole (highest pressure on artery Relaxation of ventricles- Diastole (lowest pressure on artery Lub – ventricles contract, bicuspid/tricuspid valves close Dub – semi lunar valves close, ventricles relax Heart Murmur:

10. Cardiac Conduction System Impulse begins at the SA node, travels over atria so both contract at the same time Impulse moves to the AV node to stop atria from contracting and to contract the ventricles Through AV bundle Purkenje Fibers Contraction – Apex and up.

11. Electrocardiogram (ECG) P wave – electrical activity associated with atrial depolarization QRS complex – ventricular polarizaton Twave – ventricular repolarization

12. Disorders of the heart: Pictures of heart damage Heart Transplant Surgery

13. Systemic Circulation Circulation from heart to rest of body and back to heart

14. Arteries and Arterioles Take blood away from heart Thick walls Able to expand Arterioles –

15. Capillaries – most important Microscopic tube – one cell layer thick Capillary Beds -

16. Capillary with red blood cell

17. Venules and Veins Take blood to heart Venules – drain blood from capillaries then to a vein.

18. Veins and muscle contraction Valves – allow blood flow back to heart and prevent Back flow of blood (rely on skeletal muscle contraction

19. Varicose Veins Abnormal and irregular dialations in superficial veins. Valves become weak Hemorrhoids -

20. Cause of Varicose Veins

21. Hemorrhoids

22. Disorders of : Hypertension – high blood pressure Systolic is greater than 140 mm/Hg Diastolic is greater than 95 mm/Hg Blood being pumped with too much force Decrease in the diameter of ateriole.

23. Comparison of Hearts

24. Chapter 14: Blood 3 main functions: transport, clotting, infection fighting

25. Parts of Blood Plasma: straw yellow fluid Water, nutrients, salts, wastes, gases Proteins: albumin, fibrinogin (clotting), globulins (fight infection Serum – plasma without clotting proteins

26. Formed Elements of Blood Erythrocytes (RBC’s) – involved in the transport of oxygen Hemoglobin – Protein in blood, oxygen attaches to the “Heme”

27. Iron Deficiency Anemia A diet lacking in iron.

28. Sickle-celled anemia Gentic defect in shape of blood cells. Tear-dropped shaped Abnormal shaped hemoglobin

29. White Blood Cells (formed ele) Leukocytes Have nucleus No hemoglobin Fight infection – phagocytes

30. Types of White Blood Cells Classified according to the granules in cytoplasm 1. Granulocytes- phagocytes 2. Agranulocytes – have the ability to change into a macrophage

32. Platelets (Thrombocytes) Very small in size Important for clotting

33. Blood Clotting - Hemostasis 1. Formation of platelet plug, platelets clump at wound site 2. Platelets activate prothrombin activator – enzyme that converts prothrombin into thrombin

34. Steps in blood clotting continued 3. Thrombin – solidify fibrinogen in blood plasma. 4. Fibrin forms around platelet plug 5. Blood clot with RBC’s and serum

35. Blood Types

36. Antigens An ANTIGEN is a protein or carbohydrate that acts as a signal, enabling the body to recognize foreign substances in the body.

37. Rh factor - antigen If Rh is present then Rh+. If Rh is not present then Rh-