1. Topic Refinement Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov

2. All but one of the following statements about key questions in a systematic review are true. Select the incorrect statement. A.They guide the literature search, inclusion and exclusion criteria, and types of data synthesized and reported. B.They must be clear, concise, and relevant to stakeholders. C.They are devised after the results of all relevant studies are known and pooled with other like studies. Key Questions

3. An understanding of PICOTS and the analytic framework is needed before clear, concise, and relevant key questions can be written. Which of the following terms is correctly defined? A.P= Prospective B.I= Intervention C.C= Cohort study PICOTS

4. Key informants are representatives of stakeholders who volunteer to provide input into a systematic review. Which of the following functions do they provide? A.Aid in formulating key questions that address real-world dilemmas B.Provide context to help discern content area and applicability C.Ensure transparency in the process D.All of the above Function of Key Informants

5. Which of the following groups are NOT considered to be key informants in the Effective Health Care Program? A.Clinicians B.Patients C.Industry representatives Types of Key Informants

6. Which of the following statements is true about how the public commentary process as it relates to the topic-refinement process? A.It allows all interested parties to comment on any topic-refinement project as they like. B.It is restricted to members of the public who are selected by the Agency for Healthcare Research and Quality to provide feedback. C.It allows all interested parties to comment on a particular topic, but the number of topics they can respond to is restricted. The Public Commentary Process

7. Topics for refinement should have all of the following characteristics, except: A.High priority B.Feasible C.Confirmatory Characteristics of Refinement Topics

8.  Key questions are important to the systematic review process.  Key informants should reflect the interests of stakeholders in the topic to be refined to ensure relevance and transparency.  Public commentary on key questions is a final check of relevance and ensures transparency. Summary

9. Author  This quiz was prepared by C. Michael White, Pharm.D., FCP, FCCP, a member of the University of Connecticut/Hartford Hospital Evidence-based Practice Center.  The module is based on chapter 2 in version 1.0 of the Methods Reference Guide for Effectiveness and Comparative Effectiveness Reviews (available at: http://effectivehealthcare.ahrq.gov/repFiles/2 007_10DraftMethodsGuide.pdf).