1. National Diabetes Prevention Program Director, Division of Diabetes Translation Centers for Disease Control and Prevention National Center for Chronic Disease Prevention and Health Promotion Division of Diabetes Translation Ann Albright, PhD, RD

2. 26 million with Diabetes 79 million with Prediabetes

3. Current Projections of Cases of Diabetes in the United States by 2030 millions

4. Very High Risk (A1c > 5.7%; IGT; GDM) Moderate Risk Low Risk High Risk (FPG > 100); Central Obesity; HTN, age Risk Stratification Pyramid for Diabetes Prevention 10-year risk (%) >30 % >20 % >10% >0% Prevalence (%) ~10 % ~25 % ~65%

5. Evidence for National Diabetes Prevention Program The DPP research study showed that structured lifestyle change program achieved modest weight loss of 5-7 percent and 150 min PA/wk reduced type 2 diabetes by 58% (71% in those over age 60) in those at high risk for type 2 diabetes – True for all participating ethnic groups and for both men and women – Blood pressure and lipids improved – 10-year f/u shows continued reduction in new cases of type 2 diabetes Translational studies demonstrate trained lay health workers are as effective in delivering the lifestyle change program as health professionals National DPP is 1/3 of the cost of DPP research study and demonstrates similar lifestyle change results

6. BASIC SCIENCE EFFICACY EFFECTIVENESS EFFICIENCY AVAILABILITY DISTRIBUTION Molecular/ physiological Ideal settings Real world settings Biggest effect on most people Supply Diffusion of interventions Adapted from information in Sinclair JC, et al. N Engl J Med. 1981;305:489–494. and Detsky AS, et al. Ann Intern Med. 1990;113:147-154.

8. Recent Accomplishments – Over 1200 lifestyle coaches are trained to conduct the lifestyle change program – Over 280 organizations awarded CDC recognition (pending) – Four private insurers and 280 self-funded employers covering the lifestyle change program – Work with CMS for coverage of National DPP lifestyle change program – AMA passed resolution supporting National DPP – 6 National CDC grantees

9. Source: CDC DPRP Program Data as of 3/19/2013

10. Questions & Discussion THANK YOU For more information please contact Centers for Disease Control and Prevention www.cdc.gov/diabetes/prevention 1600 Clifton Road NE, Atlanta, GA 30333 Telephone: 1-800-CDC-INFO (232-4636)/TTY: 1-888-232-6348 E-mail: cdcinfo@cdc.gov Web: http://www.cdc.gov The findings and statements in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. National Center for Chronic Disease Prevention and Health Promotion Division of Diabetes Translation