1. Minnesota Eye Consultantswww.mneye.com Outcomes of Presbyopic IOLs Parag Parekh, MD, MPA Mona Fahmy, OD David R. Hardten, MD, FACS ASCRS Poster ID: 414200 Financial Disclosure: Dr. Hardten—AMO, Allergan, Addition, Alcon, B&L, ESI, Ophtec, Refractec, Staar, TLC, VISX, VisiJet; Dr. Parekh & Dr. Fahmy: None

2. Minnesota Eye Consultantswww.mneye.com Purpose & Methods Purpose –To review the post-operative outcomes of patients undergoing presbyopic lens implantation in one or both eyes with the ReZoom, ReSTOR or crystalens intraocular lens. Methods –A retrospective analysis was performed including all Minnesota Eye Consultants patients undergoing presbyopic lens placement after cataract surgery and/or clear lens extraction between the dates of 1/1/2004 and 12/31/2006.

3. Minnesota Eye Consultantswww.mneye.com Results Overall Demographics –231 eyes of 137 patients –42% Males, 58% Females –Average age: 57.8 years IOL Breakdown –ReZoom: 86 eyes (37%) –ReSTOR: 40 eyes (17%) –crystalens: 105 eyes (45%) Indications for surgery –Cataract: 224 (97%) –Clear lens exchange: 6 (2.6%) –IOL Exchange: 1 (0.04%)

4. Minnesota Eye Consultantswww.mneye.com Results: Bilateral ReSTOR Demographics –36 eyes of 21 patients (6 male, 15 female) –Average age: 57 years –Indication: Cataract Additional Surgery –12 LASIK –2 PRK –19 YAG Capsulotomy

5. Minnesota Eye Consultantswww.mneye.com Bilateral ReSTOR Outcomes

6. Minnesota Eye Consultantswww.mneye.com Results: Bilateral ReZoom Demographics –81 eyes of 49 patients (15 male, 34 female) –Average age: 58.4 years –Indication: 79 Cataract, 1 Clear lens exchange, 1 IOL exchange Complications –1 PC Tear & Anterior Vitrectomy –2 Retinal Tears –1 Possible BRAO –1 Retinal Detachment –1 Uveitis Additional Surgery –4 LASIK –1 PRK –3 IOL exchange –15 YAG Capsulotomy –1 Scleral buckle/Vitrectomy for RD, 1 PTK for ABMD

7. Minnesota Eye Consultantswww.mneye.com Bilateral ReZoom Outcomes

8. Minnesota Eye Consultantswww.mneye.com Results: Bilateral crystalens Demographics –102 eyes of 62 patients (33 male, 29 female) –Average age: 56.8 years –Indication: 97 Cataract, 5 Clear lens exchange Complications –2 CME –5 Lens Malposition/Poor Vault –1 Capsule Contraction –2 Edge Glare Additional Surgery –17 LASIK –5 PRK –2 IOL Exchange –52 YAG Capsulotomy –3 IOL Repositioning –1 Piggyback IOL –1 CK (conductive keratoplasty) –1 Flap lift and scrape for epi ingrowth –1 ERM Peel and Vitrectomy

9. Minnesota Eye Consultantswww.mneye.com Bilateral crystalens Outcomes

10. Minnesota Eye Consultantswww.mneye.com Results: “Mixed IOL” Demographics –12 eyes of 6 patients (4 male, 2 female) –Average age: 66.3 years –Indication: Cataract Mixed IOL Combinations –2 ReZoom & crystalens –3 ReZoom & ReSTOR –1 ReSTOR & crystalens Additional Surgery –1 LASIK –4 YAG Capsulotomy

11. Minnesota Eye Consultantswww.mneye.com Results: “Mixed IOL” Outcomes

12. Minnesota Eye Consultantswww.mneye.com Conclusion Presbyopic intraocular lenses offer the possibility of functional distance and near vision, without the use of glasses in many patients. Preoperative counseling is important in setting appropriate expectations for the procedure, and additional effort in the preoperative and postoperative period is important in obtaining a good result.