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“New Options in Anterior Surgery ” Steven B. Siepser, MD January 12, 2009.

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Presentation on theme: "“New Options in Anterior Surgery ” Steven B. Siepser, MD January 12, 2009."— Presentation transcript:

1 “New Options in Anterior Surgery ” Steven B. Siepser, MD January 12, 2009

2 OUTLINE I.DSALK for keratoconus II.DSAEK for Fuch’s dystrophy III.ECP for glaucoma IV.Trabectome V.ICL for high myopia VI.CK for Presbyopia VII.Crystalens No Glasses Cataract

3 Keratoconus overview Bulging of the central cornea First appears in teens-20’s; both eyes Progressive loss of vision –Severe irregular astigmatism Management: glasses  RGP contacts  corneal transplant


5 Munson’s Sign Apical Scarring

6 Penetrating Keratoplasty  Transplant procedure  Removal of full thickness corneal button  Donor cornea and recipient  Transfer to a recipient eye PKP

7 PKP Video

8 Disadvantages of PKP “Open Sky” –Eye is open during the surgery Expulsive hemorrhage –Contents of eye are forced out by hemorrhage Increased infection rate Long recuperation period Astigmatism and suture adjustment needed Graft failure and rejection (5 %)

9 Deep Stromal Automated Lamellar Keratoplasty (DSALK) AKA “Superficial Lamellar Keratoplasty” Corneal overlay

10 Old Management –Hold off surgery –Significant loss of best corrected vision –Severe corneal scarring or thinning –Imminent Descemetocele –Contact Lens intolerance –Progressive change

11 New Management <20/30 best corrected vision Need for optimal visual acuity Difficult contact lens fitting Variable visual acuity Early intervention is best…

12 Advantages of Earlier Surgery Thicker cornea Faster rehabilitation No new astigmatism Can have LASIK / PRK later on Less chance of perforation



15 DSALK Post-Op Photo


17 Fuch’s Dystrophy Malfunction of corneal endothelium Dehydration system to maintain a clear cornea Usually females, 50’s, both eyes Guttatae –corneal swelling, folds Decreased vision, foreign body sensation, pain in morning Management: “salt” drops  bandage contact lens  surgery

18 Fuch’s Dystrophy GUTTATA

19 Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK) AKA “Endothelial Resurfacing” or Posterior Lamellar Keratoplasty

20 DSAEK Surgical Procedure Prepare endothelial graft from donor cornea Strip and peel off Descemet’s membrane of the patient Introduce graft into eye Flatten, place air bubble to allow adherence to back surface of cornea Patient should stay on back until next day


22 Advantages over Full-thickness Corneal Transplant Faster healing No stitches, therefore more predictable Safer – small incision like cataract surgery Vision clears more quickly –1-3 months vs 1-2 years for standard PKP 90% of patient’s own cornea is left

23 Video

24 SUMMARY OF NEW TRANSPLANT PROCEDURES Full thickness PKP is on it’s way out… Newer transplant procedures –transplanting the diseased portion of the cornea DSALK: anterior cornea, i.e.keratoconus DSAEK: endothelium, i.e. Fuch’s Both use a microkeratome (“automated”)

25 Glaucoma summary Fluid inside the eye is produced by a structure called the ciliary body Fluid is drained by the trabecular meshwork Pressure inside the eye is too high Damage occurs to the optic nerve Causes a slow loss of side vision

26 Treating Glaucoma DROPS –slow down the production of fluid –increase the drainage of fluid LASER – SLT: Improves Outflow –ECP: Decreases production of acqueous SURGERY –Trabeculectomy: Older opening method –Trabectome: Directly addresses outflow

27 Glaucoma-Eyemaginations

28 Endoscopic Cyclophotocoagulation (ECP) Ciliary body is cauterized with a laser to decrease production of fluid Camera inside the eye Instrument used: –Camera + light source + laser –Tiny optical fibres view, illuminate and treat the ciliary body Usually ~60 laser applications

29 ECP Often performed at the time of cataract extraction Can be performed after ALT, SLT or filtering bleb surgery A majority of patients have their pressure reduced, leading many to eliminate drops

30 ECP

31 ECP Video

32 Trabecutome Video

33 Myopic Refractive Surgery  Total US Population = 301,362,263 Myopic 75,340,000 25%  Mild (<-2.00 D)48,217,600 64%  Moderate (-2.00 to -6.00 D)24,108,800 32%  High (>-6.00 D) 3,013,600 4%  Surgeons are becoming progressively less willing to attempt LASIK in high myopes (  12 D) (U.S. Bureau of Census, International Database/Archives of Ophthalmology)

34 LASIK / PRK FOR HIGH MYOPIA Central corneal thickness < 500 um is considered thin Calculations can be performed to determine residual corneal thickness after treatment Convention is to leave >300 um “untouched” Many patients have been “turned away”

35 See What You’ve Been Missing

36 Implantable Collamer Lens (ICL) FDA Approval December 22, 2005 Dr. Siepser’s first case July 14, 2006

37 ICL Design Sits behind the patients iris (colored part) YAG PI done one week in advance –Iridectomy in the iris Foldable –Injected through a 3mm corneal incision

38 < 100 um < 50 microns 500-600 um ICL is Very Thin

39 Indications For Use STAAR Visian ICL is indicated for placement in the posterior chamber of the phakic eye for:  Correction of myopia -3.00 D to -15.00 D  Reduction of myopia -15.00 D to -20.00 D  < 2.50 D of astigmatism (toric ICL under FDA review)


41 Immediate Post-Op High “WOW factor” Not uncommon to see 20/40 or better vision at the early postop check A 2-4 hour postop check is required to check pressure

42 Accommodation – The Missing Element Cataract & refractive surgery focused on ‘Perfect’ distance vision without glasses, However….. Unable to effectively deal with loss of accommodation Patients still dependent on glasses Cataract patients want to see the same as the “young” LASIK patient and do not understand their limitation! Presbyopes – Once again are told they need to continue to wear glasses in order to see up-close (the same story 20 years later!)


44 FD04-011 rev 00 source: 1997 Baltimore Eye Study Refractive Distribution for Patients over 40 years 40.8%

45 CK for Presbyopia First time reading needs Freedom from reading glasses

46 FD04-011 rev 00 Conductive Keratoplasty ® (CK ® ) Controlled radiofrequency Stroma heats Tip = 7-O suture or human hair

47 The IOL Portfolio IOL’s come in many sizes, shapes & materials. Each has unique characteristics & capabilities Single Power Lenses Accommodating Lens Corrects only distance vision Does not accommodate in eye Glasses required Single focal point Full range of distance, intermediate & near vision Uses eye’s natural focusing mechanism Rapid visual recovery Multifocal/Defractive Lenses Multiple, fixed focal points Does not accommodate in eye Must find appropriate focal point Extensive neurological adaptation

48 Crystalens HD™

49 Video of Crystalens


51 Crystalens HD™

52 THANK YOU FOR COMING! Any questions?

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