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BASI MOLECOLARI DELLAZIONE DEL FARMACO BIOTECNOLOGIE FARMACOLOGICHE LEZIONE 12 In vivo imaging CORSO DI LAUREA SPECIALISTICA IN BIOTECNOLOGIE DEL FARMACO.

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Presentation on theme: "BASI MOLECOLARI DELLAZIONE DEL FARMACO BIOTECNOLOGIE FARMACOLOGICHE LEZIONE 12 In vivo imaging CORSO DI LAUREA SPECIALISTICA IN BIOTECNOLOGIE DEL FARMACO."— Presentation transcript:

1 BASI MOLECOLARI DELLAZIONE DEL FARMACO BIOTECNOLOGIE FARMACOLOGICHE LEZIONE 12 In vivo imaging CORSO DI LAUREA SPECIALISTICA IN BIOTECNOLOGIE DEL FARMACO Adriana Maggi

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4 Target identification and validation with reporter mice Maggi and Ciana NRDD, 2005

5 MOLECULAR IMAGING 2007 THE AVAILABLE TOOLS 2/06

6 MULTI-MODALITY MOLECULAR IMAGING IN LIVING SMALL ANIMALS Functional Magnetic Nuclear Resonance Optical imaging Bioluminescence Ultrasound MicroPET Positron emission tomography Nuclear imaging Micro SPECT single-photon emission computerized tomography 2/06 Fluorescence

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12 a 2/06 MOLECULAR IMAGING TO REVISIT ANIMAL EXPERIMENTATION IN THE RESPECT OF ANIMAL SUFFERING

13 PARTICULARLY, IN PHARMACOLOGICAL RESEARCH! ONE PICTURE IS WORTH TEN THOUSAND WORDS (Frederic Barnhard 1927) 2/06

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