1. Analytical Solution for Management of Biotech & Pharma Innovation Data collection, data warehousing, analytical design, data analysis and communication of results Joint Research Project Dr Daniel Pardo CNRS.France Dr Eric Jolivet University Toulouse 1.France Dr Andrei Mogoutov AGUIDEL.

2. Objectives Development of a complete directory of Biotech Companies and Labs in France, data collection & update tools, communication services and analytical & reporting tools

3. Related Products & Services Data collection and management of online directory « Biotech » actors in France using online questionnaire, existing databases, institutional contacts, company websites and press releases Consulting services  Positioning of companies, projects, products, patents, publications, research fields  Startup support  Early warning  Partnership network building  Advice on local promotion  Advice on foundation and management of « clusters »  Evaluation of projects  Market and technological studies  Benchmarking, competitiveness  Consultancy for valorization actors  Communication strategy development  Academic research Software solutions: On-line applications, off-line applications, customized solutions, integration of customers data, analytical tools Data analysis: Custom methods for the analysis of complex & heterogeneous datasets, text and data mining, relational analysis, GIS, scientometrics

4. Data Base of Biotech Actors in France ACTORS: Detailed information for public and private institutions  name  typology  location  contacts  HR  main financial figures  technologies  products  application areas  clinical trials  customers  partners and collaborations  company structure and history LITERATURE: Publications in biomedical journals PATENTS: biotech patents filed in patent offices

5. Design of Analytical Solution (on/offline) Back Office -data tables - textual analysis - tools for data update and control Front Office Middle Office - a layer of analytical queries - pre-defined queries for multilevel - aggregation, synthesis, indicators - graphical/analytical interfaces (GIS, Relational Mappings, Statistical Charts) - statistical tables, indicators and textual synthesis - integrated querying tools DATA UPDATEFEED-BACK

6. Back Office Patents Actors Literature Links Products Projects NETWORK ORIENTED DATABASE Technologies Clusters

7. A case study: INSERM. FRANCE Industrial Partnership Analysis Valorization & Technology Transfer Department(1980-2003)

8. Partnership of INSERM Valorization & Technology Transfer Department (1980-2003) Number of Contracts, Partners and New Partners per year

9. Main Partners of INSERM Valorization & Technology Transfer Department (1980-2003)

10. Areas of Partnership of INSERM Valorization & Technology Transfer Department (1980-2003)

11. INSERM Technology Transfer Contracts FirmsStartUpsMEOther/ Research Institutes 1980-2000 222620138 2001-2003 18667352

12. Relational Mapping Of Data Base Heterogeneous network analysis with Réseau-Lu © (www.aguidel.com)www.aguidel.com  ReseauLu Project: Data Mining & Text Mining for social sciences ReseauLu software finds patterns and relationships in data by using statistical and network analysis techniques. In addition to algorithms, the software has features to simplify the graphical representation of the data structures. The software simplifies the integration of analytical algorithms and visualization tools with database technology.

13. Main Areas of Partnership of INSERM Valorization & Technology Transfer Department (1980-2003) Per Period

14. INSERM Bio-technological Network: Areas of Partnership of INSERM vs. Companies

15. INSERM labs vs. Companies

16. “French BioIndustry” – Data Base First data set - 450 companies Preliminary data Exploratory analysis First Draft Working “Paper” – 15/06/04

17. French biotech collaboration network

18. Midi Pyrénées Region: Heterogeneous Networks Companies & Technologies of Midi Pyrénées Region “Very preliminary analysis” Source: MidiBiotech survey Next steps:  Systematic collection of exhaustive data  Scientific analysis of data

20. Additional Analysis: Scientometrix of publications database Case study : Research Community on Mental Retardation and Genetics Source – PubMed data base

21. Mental retardation & Genetics co-authorship network 2001-2004 Highly Clustered Network with mediation through individuals

22. Autism & Genetics semantic network 1964-2003 Syndromic approach

23. French biotech market structure – subset of Network of Clients Squares – subset of companies, circles – clients