1. picoSpin 45 & 80 Product Overview

2. Key Learning Fast Facts Front panel Rear panel Specifications
Inside the box
Capillary cartridge
Inside the cartridge
Cartridge, magnet, preamplifier
Software
Website resources

3. Fast Facts Worlds first miniature NMR spectrometer.
The picoSpin 80 has the highest magnetic field strength (2 Tesla) and highest resolution (20 ppb) of all known bench- top NMR spectrometers on the market.
picoSpin 45 and 80 are very similar and use common parts.
picoSpin software is hosted on the spectrometer.
The standard warranty period is 12 months from the date that the installation was accepted and signed off by the customer or 14 months from the date of shipment after the system ships from the factory or whichever comes first.
picoSpin is the world first miniature NMR spectrometer. The picoSpin 45 NMR spectrometer is a complete 45 MHz pulsed Fourier-transform liquid-phase proton NMR spectrometer in a shoebox-sized package.
To date, the picoSpin 80 has the highest magnetic field strength (2 Tesla) and highest resolution (20 ppb) of all known bench-top NMR spectrometers on the market. It provides an 82MHz resonance frequency for 1H detection and a capillary injection port, obviating the need for dedicated NMR tubes. Deuterated solvents are not required (although can be optionally used to avoid large protic solvent signals); field drift is compensated for automatically in software.
Both the picoSpin 45 and 80 includes a capillary cartridge, a permanent magnet with temperature controller and shim system, radiofrequency transmitter and receiver, digital data acquisition and signal processing, a programmable pulse sequencer, and a web browser user interface.
The picoSpin software system is hosted on the spectrometer and is ready to be used once the spectrometer is turned on and connected to any computer.

4. Fast Facts
The picoSpin is an NMR (Nuclear Magnetic Resonance) product that was acquired by Thermo Fisher Scientific in
The picoSpin 45 was introduced in 2010 and the picoSpin 80 in 2013.
The picoSpin 45 and 80 is simple enough to be installed by customers, but customers can purchase Installation and Training.
There is one (non-critical) moving part in the picoSpin 45 and picoSpin 80 NMR spectrometers.
Validation service is currently not offered.
The picoSpin is an NMR (Nuclear Magnetic Resonance) product that was acquired by Thermo Fisher Scientific in December of 2012.
In 2010, picoSpin introduced the picoSpin 45, which offered the capabilities of larger spectrometers in a much more affordable, shoebox-sized unit. Headquartered in Boulder, Colorado, the picoSpin product line is part of the Molecular business unit within the Chemical Analysis Division (CAD). The picoSpin 80 was introduced in 2013.
The picoSpin 45 and 80 is simple enough to be installed by customers, but customers can purchase a 2 hour Installation and familiarization package. It is important that customers follow the site-prep guide to install the system at least 4 hours prior to the arrival of the certified Thermo Fisher Scientific field service engineer.

5. picoSpin 45 and 80 Spectrometer Front Panel
LCD Display
Sample inlet port
Replaceable
Cartridge 5

6. picoSpin 45 and 80 Spectrometer Back Panel
Cooling Fan
ON/OFF Switch
Power Connection
+12 V: VAC
Cat-5 Ethernet
Connection
RS-232
Accessory Port 6

7. picoSpin 45 Product Features and Specs
45 MHz Pulsed FT NMR spectrometer
Proton NMR of liquids; 19F version
Better than 40 ppb typical resolution
Single-shot SNR for water > 1000
10.5 lbs total weight; 5” x 8” x 10”
Replaceable 400 µm ID capillary cartridge
20 µL sample volume
Controlled by any web browser
No cryogens, no compressed gas, etc.
No special environment
All solid-state, no moving parts
Optional 12 month license to Mnova

8. picoSpin 80 Product Features and Specs
82 MHz Pulsed FT NMR spectrometer
1H instrument
20 ppb resolution
43 lbs total weight
17” x 14” x 10”
Replaceable 400 µm ID capillary cartridge
40 µL sample volume
No cryogens, no compressed gases needed
No special environment
Solid-state technology, no moving parts
Ethernet interface; controlled by web browser
Optional 12 month license to Mnova

9. Inside the Box picoSpin 45 & 80
Embedded web server
No field replaceable parts Inside. Depot repair ONLY!
Data converters, DSP
Pulse sequencer
Rx and Tx amplifiers
Shim controller
RF preamplifiers
Permanent magnet
Magnet temperature controller
Fluid cartridge and sub-panel

10. Capillary Cartridge, Magnet, Pre-amplifier

11. Inside the Cartridge Tx/Rx Microcoil 0.4 mm ID quartz capillary
PTFE transition
Cartridge is customer replaceable

12. Capillary Cartridge picoSpin 45 & 80 picoSpin 45 picoSpin 80 Flange
20 µL sample volume
400 µm ID capillary
27 CM length
40 µL sample volume
400 µm ID capillary
32 CM length
Flange
picoSpin 45
Sub-panel
picoSpin 80

13. Software
picoSpin software is controlled by any web browser. Firefox browser is recommended.

14. Website Resources www.picospin.com www.thermoscientific.com
PRODUCT SUPPORT WEBSITE (24/7) (Thermo Scientific Employees) (Approved Distributors)

15. Summary