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Ch16 Limb Formation
Limb Disc surrounded by Limb Field
Limb Disc surrounded by Limb field What happens when limb disc is removed?
Limb Buds What determines type of limb?
Mutual Induction Effect of AER on Limb Development
AER is necessary for limb development
Sonic Hedgehog Expression
Hox Gene Expression
Feedback between AER and ZPA
Digit formation Shhh gene expression BMP concentration
Inhibition of cell death by inhibiting BMP
Which tissue controls Programmed Cell Death? Meso Ecto Duck leg + Chicken leg ? Chick leg + Duck leg ? What triggers Programmed Cell Death?
3D Substitution Model for Limb Growth and Pattern Formation Ying Zhang 1, Stuart A. Newman 2, James A. Glazier 1 1.Biocomplexity Institute, Department.
Chapter 6 Chapter 6 Development of the Skeleton Copyright © 2013 Elsevier Inc. All rights reserved.
Chapter 16- Tetrapod limb development “It is one thing to differentiate the chondrocytes and osteocytes that synthesize the cartilage and bone matrices;
Introduction To Pattern Formation Autonomous & Conditional Cell Specification, Fields & Morphogens.
Current Model for how cells become neural 1)Default state is neural 2)Local secretion of BMPs by epidermis inhibits neural fate 3)Local secretion of noggin,
Genes, Development, and Evolution
The Roles of Cell to Cell Communication in Development Lange BIOL 370 – Developmental Biology Topic #3.
Ch18 Pattern Formation – Regeneration Types of Regeneration: 1.Stem Cells (undifferentiated) 2.Morphallaxis 3.Epimorphosis 4.Compensatory Regeneration.
Lecture 19 Development and cancer “The inner life of a cell”
Development Ch 47.
Limb Disc surrounded by Limb field What happens when limb disc is removed? Is all ectoderm competent? Old vs. Young AER Which tissue determines type.
Chapter 14- Mesoderm-paraxial and intermediate
Human Hox genes 4 clusters Chr 1: 9 Hox genes Chr 7: 11 Chr 12: 9 Chr 17: 10 8 Hox genes in ancestor of bilaterally symmetrical animals Mapping Hox gene.
MCDB 4650 Limb Patterning. Which of the following is the most likely candidate for activating the expression of the different Tbx genes in the mesenchyme?
Embryology of the Hand Tom W Barwick SpR Trauma and Orthopaedics City Hospitals Sunderland.
Vertebrate Limb Patterning Chris Campbell
More evo-devo. Homeotic genes and flower formation c. 300,000 sps. of Angiosperms But Hox gene homologies even found in algae Four concentric whorls of.
Animal Development Emily Huang, Erin McGrath, Michelle Xu.
V D Latent Dorsalizing Factors The Point of Fertilization Orients the D/V Axis of the Frog.
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