1. It’s the last oral histology lecture! Please say it isn’t so… March 7, 2008 Repair & Regeneration of Oral Tissues

3. What do African termites use to “glue” their mounds together? CATEGORY: 5th grade biology & nature Macrotermes bellicosus A.Cementum B.Moss C.Saliva D.Feces E.Elmer’s glue

4. The structure is built primarily with a combination of saliva and fine-grained soil particles (coarse sand is not appropriate). Partitions within the structure are made from carton - a combination of saliva and fecal pellets Fungal gardens grow on this material (spores having been collected from the outside world). The large mounds of Macrotermes usually have tall columns which serve as air vents to regulate the inside temperature. Saliva

5. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa II.Reparative Phase III.Repair of Periodontium IV.Repair of the Tooth

6. Repair & Regeneration of Oral Tissues 2 Responses of Cells to Stimuli: 1.Adaptation 2.Death

7. Repair & Regeneration of Oral Tissues Examples of Cellular Adaptation: a) Cellular swelling (hepatitis)

8. Repair & Regeneration of Oral Tissues Examples of Cellular Adaptation: a) Cellular swelling (hepatitis)

9. Repair & Regeneration of Oral Tissues Examples of Cellular Adaptation: b) Storage of offending substance (foreign body reaction)

10. Repair & Regeneration of Oral Tissues Examples of Cellular Adaptation: c) Hypertrophy vs Hyperplasia Cardiac Hypertrophy: increased thickness of heart wall

11. Repair & Regeneration of Oral Tissues Examples of Cellular Adaptation: c) Hypertrophy vs Hyperplasia Gingival Hyperplasia: overgrowth of gingiva (dilantin)

12. Repair & Regeneration of Oral Tissues Examples of Cellular Adaptation: d)Metaplasia (respiratory tract mucosa)

13. Repair & Regeneration of Oral Tissues Examples of Cellular Adaptation: e) Atrophy (dentate vs edentulous)

14. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa Utilizes same principles as skin BUT scar tissue does not form to same degree What does this difference mean to you as dentists and dental hygienists?

15. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa What are some characteristics of scars in skin? http://www.emedicine.com/plastic/topic411.htm Color, Lack of hair/sweat appendages, Firm consistency, etc.

16. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa What are some characteristics of scars in skin? Color, Lack of hair/sweat appendages, Firm consistency, etc.

17. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa Type of wound influences healing http://surgclerk.med.utoronto.ca/WoundHeal/cases.htm This 75 year old female was attacked by a dog.

18. Repair & Regeneration of Oral Tissues www.sharkattackphotos.com/ Great White shark attack photo gallery - an attack in Aldinga Beach Australia. Victim required 462 stiches.

19. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa A.Healing by primary intention: clean, incised wound, able to approximate edges B.Healing by secondary intention: large wound, unable to approximate edges C.Healing by tertiary intention: infected wound

20. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa http://solutions.3m.com/wps/portal/3M/en_GB/skin-care/wound-resource-centre

21. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa http://solutions.3m.com/wps/portal/3M/en_GB/skin-care/wound-resource-centre

22. Repair & Regeneration of Oral Tissues I.Wound Healing in Oral Mucosa http://www.emedicine.com/asp/image Surgical closure of wound with tissue flap

23. Repair & Regeneration of Oral Tissues II. Reparative Phase http://www.emedicine.com/asp/image

24. Repair & Regeneration of Oral Tissues II. Reparative Phase What is a keloid?

25. Repair & Regeneration of Oral Tissues II.Reparative Phase What is a keloid? Beware of nonessential surgery. Keloid: “A scar that doesn't know when to stop.” Keloids are an overgrowth of scar tissue at the site of a healed skin injury.

26. Repair & Regeneration of Oral Tissues III.Repair of Periodontium Can teeth be reimplanted and remain vital? What are some potential complications? Ankylosis = fusion of tooth to bone Pulpal death = abscess, granuloma, cyst

27. Repair & Regeneration of Oral Tissues III.Repair of Periodontium

28. Repair & Regeneration of Oral Tissues lV.Repair of The Tooth Enamel? Dentin? Pulp? Cementum?

29. Repair & Regeneration of Oral Tissues IV.Repair of The Tooth

30. 95 Dead Tracts IV. Repair of The Tooth Reparative (tertiary) dentin Repair & Regeneration of Oral Tissues